CardioSource WorldNews Interventions | Page 13

Low Statin Use in People Who Need It Thyroid Hormones Linked to Cardiac Death 2.5x 2 out of 5 The number of patients with diabetes who could benefit from statin therapy to decrease the risk of future heart attack, stroke, and related death despite not being prescribed a statin. The increased likelihood that individuals with higher thyroid hormone levels—free thyroxine hormone levels—were to die of sudden cardiac death compared to patients who had lower levels. “In this study, we found 38 percent of patients with diabetes were not on a statin, which can be lifesaving,” Salim Virani, MD, PhD, cardiologist at the Michael E. DeBakey VA Medical Center, associate professor at Baylor College of Medicine in Houston and senior author. “Our study suggests more caution is warranted in the treatment of thyroid hormone replacement. Replacement therapy is often aimed at the high normal range which carries a risk of overtreatment,” said Layal Chaker, MD, MSc, study lead author. Source: American College of Cardiology. News release. Sept. 12, 2016. Source: American Heart Association. News release. Sept. 6, 2016. Poor Medication Adherence Means Higher Risks 5 million The number of Medicare Part D enrollees—age 65 and older—who do not take their blood pressure (BP) medicine as prescribed, skipping doses or ceasing the medication all together, putting them at high risks for heart attack, stroke, and death. Racial/ethnic groups and those enrollees living in Southern U.S. states, Puerto Rico, and the U.S. Virgin Islands have higher percentages of enrollees who do not take their BP medication properly. Source: Centers for Disease Control and Prevention. News release. Sept. 13, 2016. 30% Ups and Downs for CV Drug Trials The increased percentage of novel cardiovascular (CV) drugs entering Phase 3 trials between 1990 and 2012. Study authors sought to evaluate the trends of CV drugs in clinical trials over roughly a 20-year period. Their findings also showed that, between 1990 and 1995, 16% of Phase 1 trials were initiated by CV drugs, compared to only 5% of Phase 1 trials between 2005 and 2012. Source: American College of Cardiology. News release. Aug. 30, 2016. ACC.org/CSWNInterventions CardioSource WorldNews: Interventions 11