CANNAHealthcare Magazine Volume 5, 2nd Quarter, 2018 | Page 18

Healthcare Technology

& Innovation

18

Breaking down the innovative technology even further, this specialized delivery system is formed by lipid-structure carrier systems called NanoSpheres. NanoSpheres are produced by controlled mixing of phospholipids with dissimilar liquid fatty acids. Their small particle size in the nanometer range and phospholipid structure have increased solubility with more surface area, which allows for easier diffusion from the blood to the spaces surrounding the cells of a given tissue. Made from the same phospholipids that form the membranes around the cells in the human body, the NanoSpheres shield beneficial cannabinoids from dilution and degradation in the gastrointestinal tract. In this way, they are more efficiently transported intact into the circulatory system and target cells. The end result is enhanced bioavailability, improved uptake and reduced side effects, leaving consumers with beneficial results that can be felt within minutes.

NanoSpheres are made from endogenous, non-toxic components that are naturally found within the human body, making them the ideal delivery system platform for a wide range of hard-to absorb, poorly soluble and unstable ingredients. Pharmaceutical industry experts estimate that approximately 40% of lipophilic (poorly water soluble) drug candidates fail due to solubility and formulation instability. Their insolubility, degradation by digestive chemical enzymes, pre-systemic metabolism, poor intestinal absorption and removal from the liver, etc. prevents them from reaching threshold levels for activity. For these reason NanoSphere’s researchers have spent the last decade developing the NanoSphere Delivery System™ to overcome these absorption problems for a wide range of ingredients, which includes not only cannabinoids, but also nutraceuticals, pharmaceuticals, over-the-counter medications and phytonutrients. NanoSphere is poised to soon reimagine and reshape these industries as it expands its one-of-a-kind product offerings.

Advancing

Nanotechnology & Improving Cannabinoid Delivery