Research on cannabinoids has contributed to the understanding of the biological actions of these molecules and of their medical significance, in almost every bodily function and disease process. To review the research on cannabinoids for cancer therapy, go to: https://www.ncbi.nlm.nih.gov/pubmed/28948607. In the search bar, type “cannabinoids cancer” and you will see more than 1,000 medical research papers to choose from. If you want to narrow your search, specify the type of cancer, i.e., “cannabinoids breast cancer.”
Scientists have discovered that cannabis kills cancer cells in preclinical trials by using several different mechanisms of action:
• Apoptosis: the technical term for programmed cell death, or cell suicide, of cancer cells while leaving normal cells alone.
• Anti-proliferative: inhibits the rapid increase in the number of cancer cells.
• Anti-neovascularization: interferes with the formation of new blood vessels that feed the tumor.
• Anti-migration and invasion: interferes with tumor progression and migration of cancer cells.
• Anti-metastatic: inhibits the spread of cancer from the primary site.
• Anti-adhesion: inhibits the spread of cancer from the primary site.
• Down-regulates (a decrease in sensitivity) Id-1 expression: The Id-1 gene has recently been shown to be a key regulator of the metastatic potential of breast and additional cancers. The Id-1 gene is active during human embryonic (unborn) devel-opment after which it turns off and stays off. But in breast cancer, and several other types of metastatic cancer, the Id-1 gene becomes active again, causing malignant cells to invade and metastasize.
• Targeting Id-1 results in decreased tumor growth. CBD was the first non-toxic plant-based agent that could down-regulate Id-1 expression in aggressive hormone-independent breast cancer, and it also inhibits metastasis.
Watch this short video on how cannabis and cannabinoids kill cancer cells:
How and Why Does Cannabis Kill Cancer? The Science Explained
One of the outstanding cancer researchers, Dr. Christina Sanchez, explains the research they have done over the last 15 years on how the cannabinoids work to kill cancer cells:
Cannabinoids as antitumoral agents: from bench to bedside | Ch. Sánchez, Cannafest 2015
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Also, the following:
Cannabinoids asAantioxidants
and Neuroprotectants
United States Patent: 6,630,507
Hampson , et al. | October 7, 2003
http://www.patent6630507.info/
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