Cancer Updates Dec Issue Final-16006_Cancer_Updates_Dec_Issue_F4_spreads | Page 6

4 5 A Record of Accomplishments BAYLOR UNIVERSITY MEDICAL CENTER AT DALLAS AND BIIR Baylor University Medical Center at Dallas has a rich history of immune therapy innovation, especially in the area of dendritic cell research, as shown in the seminal work of the team at BIIR. Their novel treatments for colleague and mentor, Ralph M. Steinman, MD, helped him fight his pancreatic cancer for 4½ years, far beyond the median survival for this disease. Dendritic cells are keys to the immune system and vaccine development. It was the late Dr. Steinman who coined the term “dendritic cells” in 1973. In 2011, Dr. Steinman was awarded the Nobel Prize for his discovery of the dendritic cell and its role in adaptive immunity. BIIR’s oncology vaccine research facility is named after him: the Ralph M. Steinman Center for Cancer Vaccines at BIIR in Dallas. GET GLOBAL IN DEVELOPMENT OF CANCER VACCINES Since the inception of Baylor Institute for Immunology Research (BIIR) by founding director Jacques Banchereau, PhD, in 1996, BIIR has been at the forefront of developing vaccines to treat cancer. Preventive vaccines aim to stop infection from exposure to pathogens, such as viruses, parasites, bacteria, allergens and fungal infections—diseases with specific causes that originate outside the body. In contrast, cancer vaccines are therapies designed to combat tumors that form from genetic mutations inside the body. NATIONAL ‘CANCER MOONSHOT’ Ultimately, the aim of the ‘moonshot’ is to win the war on cancer—to get to a point in the very near future when we are managing cancer the same way we might manage any chronic disease. . .When we can finally stop the toxic therapies, such as chemotherapy and radiation that decimate the immune system, and instead, rally the full power of the immune system and th