There is a song about San Francisco which Scott McKenzie made. In this song, there is lyrics "If you’re going to San Francisco. ~ All across the nation. Such a strange vibration. People in motion. There’s a whole generation. With a new explanation. People in motion." I think this song just express about the mood of people who go San Francisco first.
In own my thought, San Francisco is the one of great cities in America and the world. Actually, this city have different mood around the street comparing to New York, Boston or Los Angeles. I want to say that every streets or the place in San Francisco have their own atmosphere. So I recommend you to come this city someday.