BioVoice News March2023 | Page 49

Combining a unique synergy of bioscience and engineering , Dr Tuhin Bhowmick has done some phenomenal work in the field of threedimensional functional human tissues that are intended for medical research and therapeutics . Being a first mover in this space , this young scientists has raised high hopes among both bioscience stakeholders as well as aspiring bio-engineers .

Currently , Tuhin Bhowmick is the Chief Executive Officer and Director of Pandorum Technologies , the biotechnology company he founded alongwith Arun Chandru in 2011 . With focus on tissue engineering and regenerative medicine , it is the first company in the country to design and 3Dprint human liver tissues for medical research . It is presently working on bioengineering human cornea for possible implantation with a vision to make personalized human organs such as lungs , liver , kidney , and pancreas on demand .
Under Dr Bhowmick ’ s guidance , his team has developed artificial tissue that performs the functions of the human liver . These 3-D printed living tissues enable affordable medical research with reduced animal and human trials , and will eventually lead to full scale transplantable organs .
Dr Bhowmick was previously a Research Scientist at the Indian Institute of Science from May 2012 to March 2015 . His work there focused on macromolecular structure determination , computational analyses , experimental analyses , and structure-based design . Earlier after completing his masters degree at the Maharaja Sayajirao University of Baroda in biotechnology , Dr Bhowmick finished his PhD from Indian Institute of Science ( IISc ), Bangalore . He then went on to do his Post-Doctorate from European Molecular Biology Laboratory ( EMBO-Marie Curie fellow ) in Biophysics , His subject areas included crystallography , biomaterials , structure based macro-molecular design , protein biochemistry and computational biology .
Since the outbreak of COVID-19 , Pandorum under the leadership of Dr Bhowmick has been expanding its reach by further developing the exosome platform , particularly for the post COVID19 trauma . Exosome therapy is a cell-free therapy and with the manifestation of the defined set of cargo , healing of lung tissue in COVID-19 patients could be easier . In this therapy , exosomes packed with immuno-modulatory , anti-fibrotic factors could alleviate the pain , inflammation , and pulmonary fibrosis which will lead to tissue repair .
Current Position : Chief Executive Officer & Director , Pandorum Technologies
Impact : Designed 3D functional human tissue and bioengineering human cornea for possible implantation .
Notable Awards : Top Innovator award 2017 ; ET Startup Awards ; BioExcellence Award 2016 by the Government of Karnataka
Alma Mater : Indian Institute of Science ( IISc ), Bengaluru ; European Molecular Biology Laboratory
With almost no competitors in the country , Pandorum ’ s list of awards includes the prestigious Top Innovator award 2017 at the ET Startup awards and the BioExcellence award by the Government of Karnataka in 2016 . The company received the Biotechnology Ignition Grant ( BIG ) from Biotechnology Industry Research Assistance Council ( BIRAC ), and has recently raised Rs 23 crores in Series A funding from 021 Capital , IAN Fund , Sunil Munjal and others . It is also backed by Binny Bansal and the Kotak Investment Advisory Group .

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