BioVoice News March2023 | Page 47

With over three decades of rich experience into studying microbial communities , Dr Yogesh S . Shouche has worked extensively on human microbiome of the Indian population and how it is affected by lifestyle and genetics . His research also focused on understanding microbiome alteration in diseases like diabetes , obesity , Celiac disease with the aim of developing microbe-based therapeutic solutions .

Dr Shouche is currently the Professor of Biology at Azim Premji University . Previously he was a research scientist at National Centre for Cell Science ( NCCS ), Pune , an institute affiliated to Department of Biotechnology ( DBT ), Government of India . At NCCS , Dr Shouche developed a microbial culture collection that harbours microbes from different ecosystems , specialised microbes ( cyanobacteria , anoxygenic photosynthetic bacteria , anaerobes and antibiotic-resistant microbes ). This is the largest culture collection globally under one roof and is also International Depositary Authority ( IDA ) under the Budapest Treaty and Designated Repository under the Biological Diversity Act 2002 of India . The other microbial ecosystems that he worked on are effluent treatment plants , impact of mass bathing event ( Kumbh Mela ) on the river ecosystem and stratosphere besides microbial resistance to antimicrobials and antibiotics .
Exploratory investigations carried out by Dr Shouche and his group at the NCCS have provided glimpses into the changes occurring in the gut microbiota during the two vital stages in human life-- pregnancy and infancy . They studied the gut microbial communities from twenty healthy Indian mother-infant dyads at different stages of pregnancy and early infancy , using tools of molecular biology , called high throughput 16S rRNA gene sequencing . Unlike other similar studies done with the Indian population , which were mainly intervention-based or disease-associated investigations , Dr Shouche ’ s group studied the gut microbial profiles in healthy mother-infant dyads , which therefore reveal the types of
Current Position : Professor , Azim Premji University
Impact : Developed a microbial culture collection that harbours microbes from different ecosystems , specialised microbes .
Alma Mater : University of Pune ; Indian Institute of Science , Bengaluru organisms associated with normal health conditions in pregnancy and infancy .
Dr Shouche has published more than 150 research paper in reputed journals of relevant area . He has served on the editorial boards of Current Science , Scientific Reports and PLOS One . He has reviewed publications in International journals like FEMS Ecology , International Journal of Systematic and Evolutionary Microbiology , Microbial Ecology and others . Dr Shouche has several national and international collaborations ; and more than 25 successful grant applications from various funding agencies .
Dr Shouche ’ s major area of interest is microbial communities in unique ecosystems and how they interact with each other and their surroundings . He has keen interest in science popularization and has written several articles in English as well as Marathi newspapers and magazines , besides giving talks on radio , at schools , colleges and public events .

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