Researchers identify the elusive gene of a critical enzyme in the synthesis of apiin , an important plant compound with potential medicinal uses
By Sachin Arya
Newly discovered plant gene that helps make Apiin
Researchers identify the elusive gene of a critical enzyme in the synthesis of apiin , an important plant compound with potential medicinal uses
By Sachin Arya
Apiin , a natural compound found in high amounts in parsley and celery , is thought to have important medicinal properties . However , producing apiin is difficult because the gene that codes for apiosyltransferase , an important enzyme in apiin synthesis , was unknown . In a recent study , scientists from Japan successfully identified this gene in celery . Their findings will pave the way to biosynthesis platforms to produce apiin , which in turn will help us clarify its natural role and medical applications .
The herbs celery and parsley are widely used for medicinal and health purposes by humans due to their numerous health benefits . The medicinal uses of these plants date back to the ancient Greeks , Egyptians , and Romans . Although scientists have not yet identified their main active compounds , some believe " apiin " may be one of them . There is some evidence that apiin , classified as a flavonoid glycoside , has proven anticancer and anxiolytic properties in humans . Additionally , celery and parsley produce this compound in large amounts as compared to other plants . Biologists have hypothesized that apiin offers antioxidant , anti-UV light , and insect repellent effects , thus serving essential biological and ecological roles .
However , to prove any of these claims with certainty , we need to find a way to produce apiin in large amounts . While scientists have identified the genes of almost all the enzymes that partake in apiin synthesis , the final piece of the puzzle is still missing . The gene for apiosyltransferase ( ApiT ), the enzyme which participates in the final step of apiin production , is still unknown .
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