directly to the respiratory system including administration by inhalation . The investment will facilitate a long-term strategic partnership between Cipla and Ethris for the development of messenger RNA ( mRNA ) -based therapies and fast-track Cipla ’ s participation in the mRNA space , enabling it to provide access to cuttingedge solutions developed by Ethris for the developing countries . Umang Vohra , MD & Global CEO of Cipla , said : “ This collaboration accelerates our innovation journey and enables us to provide access to cutting-edge healthcare solutions to our patients .”
CDRI scientist finds out a novel option to tackle Triple-Negative Breast Cancer metastasis
India is known as the Triple-Negative Breast Cancer ( TNBC ) capital of the world owing to its high incidence . TNBC is the deadliest amongst all breast cancer subtypes with few therapeutic options . This type of cancer is associated with early metastasis resulting in poor five-year survival rates . Dr Dipak Datta ’ s research group at CSIR-CDRI has recently published an article in a peer reviewed international journal , Nature Communications 13 , 7344 ( 2022 ), that uncovers new functions for epigenetic modulator EZH2 ( Enhancer of Zeste homolog 2 ) in the spread ( metastasis ) of TNBC . ( An epigenetic modulator
regulates whether a gene will be expressed or not ). Using an inhibitor of EZH2 , Tazemetostat , Dr Datta and team have demonstrated a new and interesting mechanism for EZH2 mediated gene upregulation that can dictate TNBC progression .
Thermo Fisher Scientific launches big foot cell sorter in India
Thermo Fisher Scientific , the world leader in serving science , has announced the launch of the Bigfoot Spectral Cell Sorter in India . The first-ofits-kind cell sorting technology provides easy to use , high-speed cell sorting by complimenting conventional with spectral sorting and analysis . Cell sorting enables scientists to isolate live , homogenous cell populations to answer critical questions regarding cellular changes that take place under certain conditions , stem cell differentiation , and cellular response to drugs . These insights are useful in genome editing , vaccine studies , drug and toxicity screening , and cell and gene therapy development , among other applications . “ The Bigfoot Spectral Cell Sorter addresses researchers ’ need to gain deeper biological insights and advance their work in the development of new therapies ”, said Amit Chopra , managing director , India and South Asia , Thermo Fisher Scientific .
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BioVoiceNews | February 2023