Biosequence Searching Expert Reports by Ingenious Ebrain chemical structure sequence search

Chemical Structure & Sequence Search
Sequence Searching
Due to advent of a latest Molecular Biology techniques number of sequences filed
in patent documents are increasing with a high momentum. Majority of the sequence listings
present in the patent documents are the sequences used for diagnostic purposes such as EST
sequences and probe/primer sequences; treatment purposes such as natural/synthetic
genes/peptide sequences and siRNA sequences; and genes/proteins involved in specific
biochemical pathways such as genes /proteins responsible for biofuel / industrial enzyme
production.
Our biosequence searching team is well equipped for conducting all types of sequence searching
(exact, subsequence and using all industry standard databases such as REGISTRY / CAPLUS /
DGENE / PCTGEN / USGENE databases hosted by STN and Genome Quest. We are experienced in
conducting sequence-searching projects for the following Biotech / Pharma domain-related
biosequences:
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Probe/primer sequences
Antibody sequences
Gene/protein sequences involved in
Therapeutic peptide sequences
Vector sequences
Mutated gene/protein sequences
Analogous sequences for identifying
miRNA / siRNA sequences
biochemical pathways
corresponding mutation locations
Sequence Listing Preparation
We are capable of preparing nucleotide and amino acid sequence listings as per the following:
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WIPO standard for the presentation of
nucleotide and amino acid sequence listings
in patent applications
(ST.25)
USPTO sequence rules under 37 C.F.R.
§§1.821-.825 published on June 1, 1998, entitled
“Requirements for Patent Application
Containing Nucleotide Sequence and Amino Acid
Disclosures” (see Federal
Register 63:104, 29620-29643)
Corresponding equivalent rules in other
jurisdictions
We prefer to receive complete patent details for preparing cost effective sequence listings in PTO
acceptable format. We advise our clients to claim only the key innovative sequences and mention
all other relevant sequences in full specifications. Our experienced professionals support our clients
in finalizing relevant sequences that can be claimed/mentioned in the patent applications.
Structure Searching
Chemical compounds form key ingredients of the pharmaceutical drugs and have in numerous
other applications in our routine life. Planned structure searching in patent and non-
patent document with a thorough knowledge of substance databases and structure search engines
is a key challenge area for IP professionals.
Our chemical structure searching team has expertise in conducting all types of structure searching
(exact, substructure, similar structure, fragments and Markush structure) using well-known
industry standard databases such as REGISTRY / CAPLUS/MARPAT hosted by STN, Merged
Markush Service (MMS) and Beilstein. Our professionals can perform in-depth analysis of Markush
structure and are capable of searching chemical compounds by molecular formula, CAS Registry
Number, ring size, and other chemical attributes.
We are experienced in conducting structure-searching projects for the chemical compounds that
have been used as constituents of the following:
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Drugs
Reaction buffer Detergents
Toothpaste