Biomet 3i Brochures Site Preparation & Surgical Technologies | Page 11

Introduction Surface Technologies The NanoTite™Implant Family The NanoTite Implant is the patented OSSEOTITE® dual-acid-etched surface, which is then further treated with a deposition of nanometer scale crystals of calcium phosphate. This is known as the Discrete Crystalline Deposition or DCD® Process. The surface treatment is a discrete crystalline deposition on the OSSEOTITE Surface, not a plasma sprayed coating. NanoTite Surface at 20,000x magnification The synergistic effect of these two technologies, the OSSEOTITE Surface and the DCD Process has demonstrated promising results in animal studies.* Because of this synergistic effect, a more complex micro-surface is created. Preclinical studies* demonstrated that the NanoTite Surface treatment, when compared to OSSEOTITE Control Implants, significantly improved the rate and extent of bone-to-implant contact, resulting in statistically significant enhanced integration.1,2 For all NanoTite Configurations, wherever there is the dual-acid-etched OSSEOTITE Surface, the DCD nano-scale calcium phosphate has been applied. 1. Mendes VC, Davies JE†. Discrete calcium phosphate nanocrystals enhance osteoconduction on titanium-based implant surfaces. Canadian Biomaterials Society. 25th Annual Meeting. May 26-28, 2006. Calgary, Alberta, Canada. 2. Mendes VC, Davies JE†. Discrete calcium phosphate nanocrystals render titanium surfaces bone-bonding. Int J Oral Maxillofac Implant. 2007;22:484. *Pre-clinical studies are not necessarily indicative of clinical results. The OSSEOTITE® Implant Family The OSSEOTITE Implant features the patented dual-acid-etched surface that is optimal for improving the clot/implant attachment, which may increase platelet activation and red blood cell (rbc) agglomeration.1 OSSEOTITE Surface at 20,000x magnification For more than 15 years, with documentation from numerous global multicenter clinical evaluations,2-9 the OSSEOTITE Surface has proven to be one of the most predictable and well-researched surfaces ever. Clinical studies on the OSSEOTITE Surface document the benefits of increased contact osteogenesis, especially in poor quality bone.10 1. Park JY, Davies JE†. Red Blood Cell and Platelet Interactions with Titanium Implant Surfaces. Clinical