BIKERS CLUB APRIL 2020 ISSUE | Page 26

B I K E R S C L U B ® | www.bikersclub.in Other coronaviruses were responsible for deadly outbreaks of Serious Acute Respiratory Syndrome (SARS) in china in 2003 and Middle East Respiratory Syndrome (MERS) from 2012. These viruses mutate relatively often in ways that allow them to be transmitted to humans. An Infinity of Viruses If you get sick with the flu, for example, every infected cell in your airway produces about 10,000 new viruses. The total number of flu viruses in your body can rise to 100 trillion within a few days. That's over 10,000 times more viruses than people on Earth. If there can be so many viruses in a single person, how many viruses are there in total on our planet? As in over 10 million times more viruses than there are stars in the universe. As in, if you were to stack one virus on top of another, you'd create a tower that would stretch beyond the moon, beyond the sun, beyond Alpha Centauri, out past the edge of the Milky Way, past neighbouring galaxies, to reach a height of 200 million light-years. Now it seems that I may have been lowballing that number. Scientists don't come up with a number like 1031 by counting every single virus on Earth. They take surveys in different environments-the soil, the water, the ocean floor-and then extrapolate. As they take more samples, they can adjust their estimate up or down. It used to be that scientists could only conduct these surveys by squinting down a microscope and actually spotting the individual viruses. That turns out to be a bad way to count viruses, in part because their hosts- such as bacteria and protozoans-often don't grow in the artificial confines of a laboratory. Without viable hosts, the viruses can't reproduce, and so they go unnoticed. Things got a lot better once scientists found a new way to count. Instead of looking for full-fledged viruses, they just looked for pieces of their DNA. The ocean, once considered a desert for viruses, turned out to be a broth of viral DNA. Given the sheer volume of the ocean, most of the world's viruses reside there. And most of the viruses that scientists discovered in the ocean turned out to be parasites of bacteria, known as bacteriophages. But scientists have long known that there's another kind of virus out there, one that uses a somewhat different molecule for its genes. DNA is a double helix, which encodes genes along both strands. When our cells make a protein from a gene, they make a copy on a single-stranded molecule called RNA. DNA-encoded genes can also make RNA molecules that do other jobs, such as sensing the concentration of various elements inside a cell. In some viruses, RNA also takes on DNA's job and encodes genes. Influenza is just one example of the many RNA viruses out there (or in you). Unlike bacteriophages, RNA viruses almost never infect bacteria. Instead, they infect us, plants, fungi, protozoans-all members of the same great lineage of life known as eukaryotes.