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Early during pregnancy , developing oocytes ( eggs ) in female fetuses are arrested in Prophase I . Resumption of development does not occur until a woman enters puberty , and even then , only a few eggs finish development each month .
1 . At the age of 42 , how long has a woman ’ s remaining eggs been stalled in Prophase I ?
2 . During both Anaphase I and Anaphase II of Meiosis , chromosomes are separated by a process called disjunction . What types of errors can occur at this time and what are the consequences ?
3 . How might your answers to the two questions above be related to the increased incidence of Down syndrome among children born to older women ?
Briefly describe the cell cycle and explain how it is regulated .
How might disruption of the cell cycle lead to cancer ?
Find and describe the actions of a chemotherapeutic agent that directly targets the cell cycle . Be sure to explain specifically when during the cell cycle it works and what it interferes with .