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Early during pregnancy, developing oocytes( eggs) in female fetuses are arrested in Prophase I. Resumption of development does not occur until a woman enters puberty, and even then, only a few eggs finish development each month.
1. At the age of 42, how long has a woman’ s remaining eggs been stalled in Prophase I?
2. During both Anaphase I and Anaphase II of Meiosis, chromosomes are separated by a process called disjunction. What types of errors can occur at this time and what are the consequences?
3. How might your answers to the two questions above be related to the increased incidence of Down syndrome among children born to older women?
Briefly describe the cell cycle and explain how it is regulated.
How might disruption of the cell cycle lead to cancer?
Find and describe the actions of a chemotherapeutic agent that directly targets the cell cycle. Be sure to explain specifically when during the cell cycle it works and what it interferes with.