Baylor University Medical Center Proceedings April 2014, Volume 27, Number 2 | Page 105

Selected published abstracts of Baylor researchers
AMERICAN JOURNAL OF CARDIOLOGY
Morphologic features of cardiac sarcoidosis in native hearts of
patients having cardiac transplantation
Roberts WC, Chung MS, Ko JM, Capehart JE, Hall SA
Am J Cardiol 2013 Nov 23 [Epub ahead of print]. Reprinted with
permission from Elsevier.
Described herein are 10 patients who underwent cardiac transplantation (CT) for severe chronic systolic heart failure resulting from
cardiac sarcoidosis. None had the diagnosis of sarcoidosis established
before CT except for the 3 patients who earlier had had a portion of
left ventricular wall excised for insertion of a left ventricular assist
device and non-caseating granulomas were present in the removed
myocardium. Although none of the 10 patients had significant narrowing of any of the epicardial coronary arteries, all had focal scarring
of the walls of the left and right ventricles and ventricular septum and
all had dilated ventricular cavities. The patients with the most ventricular wall scarring tended to have the fewest sarcoid granulomas in
the ventricular walls. Two patients had no sarcoid granulomas in the
excised heart although one did have typical sarcoid granulomas in the
portion of left ventricular wall excised to insert a left ventricular assist
device. Patients with cardiac sarcoidosis severe enough to warrant CT
had characteristic cardiac ventricular morphologic findings, and no
dysfunction of other non-cardiac organs, making clinical diagnosis of
cardiac sarcoidosis rather difficult.

BRITISH JOURNAL OF CANCER
Efficacy and safety of sunitinib in elderly patients with
metastatic renal cell carcinoma
Hutson TE, Bukowski RM, Rini BI, Gore ME, Larkin JM, F