Autistic Spectrum Digest (Autism) Issue 7, May 2014 | Page 9

Research in review New spliced autism gene variants identified Lipid levels impact autism during pregnancy In path-breaking new study at the University of California, San Diego School of medicine, researchers have isolated new autism gene variants in human brains which were not identified previously because of their spliced forms. The protein products of these new genes were screened against many thousand other proteins and their interactions noted. A study conducted at the York University revealed its findings that elevated lipid levels during pregnancy might be a trigger for autism. The researchers found that two vital neural pathways of the early intra-natal development might be affected by abnormal lipid molecule levels of the brain. They also said that cosmetics and certain over-the-counter medications used commonly can alter these lipid levels and might be a contributory factor indirectly for autism. Study sparks debate of risk of autism in boys following prenatal exposure to SSRIs That drugs have side-effects, we are all aware of, but side-effects that can damage a child forever are a complete no-no. Researchers from the John Hopkins Bloomberg School of Public Health along with teams from the University of California, Davis’ MIND institute studied 1000 mothers. They arrived at a conclusion that the risk of developmental problems like autism was three times higher in boys in cases of prenatal exposure to SSRIs. Paternal obesity potential risk factor for autism A study conducted by the Norwegian Institute of Public Health found that obesity in the father could be a higher risk factor for autism in the child than maternal obesity. Study finds prenatal molecular roots for autism and neuropsychiatric conditions A study from the prestigious Yale University announced this week about a solitary molecular mechanism that was responsible for triggering brain cells and leading to neuropsychiatric disorders. The team of scientists exposed mice embryos to common toxins like alcohol, methyl mercury and maternal seizure-like processes and found that the developing brain activated a single gene they have named as HSF1 or Heat Shock Factor -1 which protects the brain from these insults