Australian Doctor Australian Doctor 27th October 2017 | Page 5

‘ No’ can be hardest word for IVF clinics

MICHAEL WOODHEAD FERTILITY clinics need to address the difficult issue of telling older women they should stop futile IVF treatment, a fertility specialist says.
With IVF clinics promoting their success rates in achieving pregnancy, some women over 40 believe they can defy biology and conceive, says Professor Bill Ledger, head of obstetrics and gynaecology at the University of NSW.
Despite technological advances, the reality was that many women over 40 would never have a child through assisted reproduction, he told the Fertility Society of Australia annual conference in Adelaide.
“ At times there is an element of self-delusion about the chances of success from IVF … some older women explain that they have healthy lifestyles. But physical health has no influence on egg
health or egg reserve,” he said.
“ There are some things science can’ t help you with. We can’ t beat biology.”
The chances of pregnancy fell
to about 10 % at age 42 with IVF treatment and could be as low as 1 % for some women, he pointed out.
Professor Ledger said he did
‘ Emotions are very deep, the tears come and a lot of us, including me, will often give in and say, okay, just have one more go.’
— Professor Bill Ledger, head of obstetrics and gynacaecology at the University of NSW
not believe commercial IVF clinics were offering women false hope of success, but that demand for treatment was patient-driven.
Despite clinics providing women
with clear statistics on the low chances of success, some women were determined to keep trying, he told Australian Doctor.
“ Having a family is one of the most fundamental desires, so telling people to stop is a very tough thing and we don’ t always do it well,” he said.
“ Emotions are very deep, the tears come and a lot of us, including me, will often give in and say, okay, just have one more go.”
GPs could play an important role in providing psychological support for the grief that women experienced after stopping assisted reproductive technology, he said.
“ The woman will finish her contact with the clinic, yet will still have unmet need.
“ Often they and their partner have a long-term relationship with a GP practice which is much deeper and holistic than their relationship with us.”

In Brief

Staff writers
Free flu vaccine for Queensland children
GPs in Queensland can give free flu vaccines to children aged six months to five years old next year, the state government says. Minister for Health Cameron Dick said the severe 2017 flu season saw 544 children hospitalised, which prompted the government to offer vaccines to up to 300,000 children across the state in a $ 1 million program for 2018.“ Queensland will also push for inclusion of the free flu vaccine for under fives on the national immunisation program,” he said. Rapid point-of-care testing for influenza will also be funded in Queensland hospitals as part of a plan to prevent unnecessary admissions and reduce prescriptions of antibiotics and antiviral medications.
Doubts over accuracy of non-fasting LDL-C LDL cholesterol levels may be misclassified in one in 14 patients when non-fasting measures are used, according to US research. A study at Johns Hopkins University School of Medicine found non-fasting measures of lipids were particularly inaccurate compared with fasting measures when LDL-cholesterol levels were in the target range of under 1.8mmol / L. Researchers said a new, more accurate method to calculate LDL cholesterol was available. Circulation 2017; online.
Epilepsy drug safe in pregnancy, study concludes THE anticonvulsant lamotrigine is generally safe for use in pregnancy, according to a long-term Israeli study. No major malformations were seen in the children of 83 women who took the drug in the first trimester of pregnancy, a study from a single tertiary centre found. There were also no neurodevelopmental disorders seen in the children up to the age of 12. In Australia, lamotrigine is category D, the secondhighest risk category of the TGA database for prescribing in pregnancy. This is for“ drugs which have caused, are suspected to have caused or may be expected to cause an increased incidence of human fetal malformations or irreversible damage”. British Journal of Clinical Pharmacology 2017; online.

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