Australian Doctor Australian Doctor 27th October 2017 | Page 10
A positive addition in depression management
Neurofolin ® *
*
1
SSRIs
For the dietary management of depression
Neurofolin contains L-methylfolate – an active form of folate 2
that addresses a part of a complex deficiency found in sufferers
of depression. 3,4
More bioavailable than synthetic folic acid, 5 it efficiently crosses
the blood-brain barrier to promote the synthesis of mood-
regulating neurotransmitters like serotonin. 2 When added
to SSRIs, L-methylfolate offers real cause for optimism. 1
Find out more at neurofolin.com.au
Only available in pharmacies
Neurofolin is for the dietary management of depression and should be used under medical supervision.
References: 1. Papakostas GI, Shelton RC, Zajecka JM, et al. L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials. The American Journal of Psychiatry.
2012;169(12):1267–1274. 2. Stahl SM. L-methylfolate: a vitamin for your monoamines. The Journal of Clinical Psychiatry. 2008;69(9):1352–1353. 3. Shorvon, S, et al. The neuropsychiatry of megaloblastic anaemia. British Medical Journal.
1980;281:1036–1038 4. Young SN. Folate and depression–a neglected problem. Journal of Psychiatry & Neuroscience 2007;32(2):80–82. 5. Willems FF, Boers GH, Blom HJ, et al. Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate
and folic acid in patients with coronary artery disease. British Journal of Pharmacology 2004;141(5):825–830. Neurofolin ® is a registered trademark. Metafolin ® is a registered trademark of Merck KGaA, Darmstadt, Germany. Made by Grunbiotics
Pty Ltd. Distributed by Mylan Health Pty Ltd trading as Mylan Health (ABN 29 601 608 771) of Level 1, 30 The Bond, 30-34 Hickson Rd, Millers Point, NSW 2000, Australia. Ph: 1800 314 527. NEU-2017-0007. August 2017. GRUN0010.