Australian Doctor Australian Doctor 2 June 2017 | Page 7

COMMENT paul smith LAST week, Minister for Health Greg Hunt chose — wisely or not — to give his first major speech after the budget, which was a disap- pointment to many GPs, to a roomful of doctors at the AMA’s annual conference. Two opposing political narratives currently surround the health budget. Labor says it’s all about continuing the cuts. But Mr Hunt’s stance is that the re-indexation of Medicare — the pledge to slowly thaw the freeze — is a winner for the specialty. When Australian Doc- tor later put the question to him that GPs didn’t see it that way, his response was unsurprising. He referenced those pre- budget “written agreements” he had secured with the RACGP and AMA. Hunt says re-indexation is a win for general practice The Minister for Health, Greg Hunt, addressed the AMA conference last week. the comments of GPs.” (‘GPs’ “The indexation is what seems to be his shorthand for has been sought and I can the RACGP). only refer … to the written So these pacts, the cause partnerships. This is all evi- of fraught discussion, are dence that [re-indexation] is being used as the minister’s of fundamental importance.” gold shield to the accusations Mr Hunt claims the budget that indexation fixes nothing, offers $550 million in “GP that it’s still slowly eroding support” over the next two patient rebates for GP care. years. In a fluent performance “It’s a very significant before the AMA faithful, Mr increase that has been backed Hunt made one other impor- by the written agreement tant point — his ambitions with the GPs and backed by for Health Care Homes. He dropped heavy hints the scheme would evolve to embrace pay-for-perfor- mance. The pilots will receive capitation payments of up to $1800 a year to look after complex chronic disease patients. But this may not be forever. “We should be moving to much more genuine outcome payments in the Health Care Home model … I’m flexible. This is a trial. It is not the end of it. We can improve the model,” Mr Hunt said. Whether pay-for-perfor- mance is the way to do it, will be another hot debate for the future. Even those doctors who signed his ‘peace in our time pacts’ will be seeking something much less con- troversial for Health Care Homes: real investment. The AMA’s National Conference took place in Melbourne on 26-28 May. Medical cannabis cuts seizures in severe epilepsy, study shows rada rouse NEJM Medical cannabis has been shown for the first time in a randomised clinical trial to alleviate convulsive seizures in children with epilepsy. The findings add weight to anecdotal accounts that cannabidiol can stop recurrent drug-resistant seizures, say the researchers, although they note the high rate of adverse events and drop-outs from the active arm. The trial in 120 children with Dravet syndrome (a genetic form of epileptic encephalopathy) shows three children (5%) became completely seizure-free after taking cannabidiol for just over three months, compared with none in the placebo group. And in another 40% of participants, the frequency of convulsive seizures fell by 50%, compared with 27% for those on placebo. However, no significant reduction was seen in non- convulsive seizures. Professor Ingrid Scheffer, chair of paediatric neurology at the University of Melbourne and director of paediatrics at Austin Health, is a member of the international team of investigators. She says the study proves cannabidiol is effective in severe epilepsy. “I am delighted that we finally have high-level evidence that cannabidiol is effective for uncontrolled seizures in Dravet syndrome. The next question is whether cannabidiol is effective in other forms of epilepsy,” she says. The trial, funded by GW Pharmaceuticals, saw participants given either 20mg of oral cannabidiol solution per kg of body weight plus usual therapy, or placebo and usual therapy. Overall, 62% of those in the cannabidiol group saw an improvement in their condition by at least one category on a seven-category scale, compared with 34% of those on placebo.. However, adverse events were more common in the cannabidiol group and included diarrhoea, somnolence and abnormal liver function tests. Eight patients receiving the active drug withdrew from the study compared with one patient on placebo. Further trials of cannabidiol were already underway in other groups of patients with epilepsy, Professor Scheffer said. New England Journal of Medicine 2017; online. Counsel about psoriasis in pre-pregnancy ANTONY SCHOLEFIELD WOMEN with psoriasis should consider pre-pregnancy counselling because of the complex issues they might face, including the need for medication review, experts say. New guidance for doctors on managing pregnant women with psoriasis has been drawn up by the Australasian Psoriasis Collaboration, a group of dermatologists with input from a clinical geneticist. The advice, published in the Australasian Journal of Dermatology, includes more detailed information about psoriasis medications in pregnancy than that provided by the Australian Drug Evaluation Committee’s categorisation system, the authors say. They suggest women should consider counselling prior to conception. The risk of the child inheriting psoriasis is small, just 16% if one parent has the disease, but 50% if both parents have it. Other health risks are disputed, with some studies showing that women with psoriasis are at increased risk of preterm or low-birth-weight babies, as well as miscarriage. However, other studies show no increased risks. Psoriasis often improves during pregnancy and flares in the weeks following birth, but about one-quarter of women report that psoriasis worsens in pregnancy, the guide says. Women with psoriasis are, however, more likely to have other risk factors, such as high BMI, depressive symptoms or a smoking habit than women without psoriasis. The guide also warns doctors to be cautious when offering live vaccines for neonates due to potential exposure in utero to anti-TNF biologic therapies. It adds that doctors should prefer well-established anti- psoriatic drugs, as newer ones might have only limited fetal and maternal safety data, in particular for possible behavioural teratogens. The guidelines, produced with an unrestricted grant from AbbVie, include a full list of medications. Australasian Journal of Dermatology 2017; online. www.australiandoctor.com.au 2 June 2017 | Australian Doctor | 7