Australian Doctor Australian Doctor 2 June 2017 | Page 14
A big drinker with
visual disturbance
THE AUTHOR
Grand Rounds
HEPATOLOGY
Alcohol dependence, obesity and impaired glucose
tolerance make a toxic cocktail for this patient.
Dr Penny Gosling is a GP
registrar in Canberra and
Jerrabomberra, ACT.
M
ARK, 52, presented with concerns
over several months of visual distur-
bance. He described a distortion of
vision not cleared by blinking.
Past medical history
Mark’s past history included obesity, obstructive
sleep apnoea, impaired glucose tolerance, hyper-
cholesterolaemia and known alcohol dependence.
He was under the care of a psychologist to help
reduce his alcohol intake.
Baseline gamma-glutamyltransferase (GGT) was
around 600 (RR: 5-50) and he had previously been
counselled on the risk of liver damage.
Mark lived with his supportive family and young
children, and functioned at a high level in employ-
ment.
Assessment
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Initial assessment revealed marked new scle-
ral icterus and jaundice. There appeared to be a
marginal left proptosis. Visual acuity was 6/16
uncorrected. Mark had never previously required
corrective lenses.
Further systemic examination revealed relative
haemodynamic stability. Heart rate was 96, res-
piratory rate 18 and BP 122/77 (marginally lower
than baseline). There was a fine tremor and when
specifically elicited, hepatic asterixis. Abdomi-
nal examination