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44 HOW TO TREAT : MEDICAL DISORDERS IN PREGNANCY

44 HOW TO TREAT : MEDICAL DISORDERS IN PREGNANCY

3 NOVEMBER 2023 ausdoc . com . au
Figure 1 . The final step is a discussion with the woman and her partner regarding the risks , benefits , and likely outcomes of pregnancy , given the particular medical situation .
pharmacist assistance to inform
shared decision-making .
Perform a baseline assessment of
the medical condition , so that any deterioration during pregnancy can be evaluated . This may require repeated imaging , blood tests , urine tests , cardiological or respiratory studies , or a range of other baseline investigations .
Providing information
The final step is a discussion with the
woman and her partner , if applicable , ( see figure 1 ) regarding the risks , benefits , and likely outcomes of pregnancy , given the particular medical situation . The author generally breaks this discussion into four parts ( see box 1 ). Often answering these questions and giving sound advice to women and their families will involve a literature
Box 1 . Issues to discuss with the woman and her partner
1 . What is the likely impact of pregnancy on the medical condition , and subsequent morbidity and mortality ?
2 . What is the likely impact of the medical condition on pregnancy , birth and neonatal outcomes , in the short and long term ?
3 . If after considering the risks and benefits , the woman wishes to try to conceive , how do we maximise the chance of good outcomes ?
4 . If natural conception is not possible , in this situation , is assisted fertility a reasonable choice , given the woman ’ s situation ?
woman and her partner will decide that a pregnancy is too risky . This can be associated with very significant grief , and may need multidisciplinary care , including the support of social workers or psychologists . For some women , motherhood defines womanhood , and there may be considerations relating to family expectations , cultural practices , religious background , and a sense of meaning and purpose that need to be resolved in coming to terms with not being able to have a baby . These need time and sensitivity .
APPROPRIATE CONTRACEPTION FOR WOMEN WITH MEDICAL ISSUES
DURING preconception care , espe-
affected by pregnancy with a real risk of maternal death ( such as , pulmonary hypertension , some congenital cardiac anomalies ), women who are taking medications that are not appropriate in pregnancy ( for example , women on medications such as statins , ACEIs , ARBs , bisphosphonates , mycophenolate , methotrexate , monoclonal antibodies , sodium valproate and other antiepileptic drugs , isotretinoin , tetracyclines , NSAIDs , warfarin ), or where pregnancy is inadvisable for psychosocial or other reasons .
PRECONCEPTION CARE FOR MEN
WHILE we focus on preconception
care for women , we tend to neglect the reproductive health and precon-
surgical issues , migraines , metabolic syndrome and thromboembolic disease . In some cases , specialist preconception advice may assist .
Specialist care may be required
Women with conditions such as the
ones listed in box 2 are likely to benefit from referral to a tertiary centre with expertise in obstetric medicine for preconception and pregnancy care . If in doubt , it is far better to refer unnecessarily than to have to care for a pregnant woman who did not have adequate preconception care . Many major centres now offer telemedicine , which makes these specialist services accessible to women throughout rural and regional Australia . Telemedicine services also offer the benefit of bet-
review , as the outcomes of pregnancy
cially in high-risk settings , adequate
ception care of men . A 2019 review
ter supporting GPs providing obstet-
in various medical conditions is con-
contraception is critical . Document
by Kothari et al outlines the impor-
ric services in regional and rural
stantly improving .
partner and family or key supports , as
contraception advice at each pre-
tant issues regarding men ’ s health
communities .
Helping women understand risk
Where there is significant risk of serious
adverse outcomes , such as the risk of maternal or perinatal mortality , or severe morbidity , it is good
they may end up caring for a baby without a mother . In addition , usual end of life planning , such as the preparation of wills , advanced health directives and appointment of health power of attorney is important .
To help people understand risk , it
conception visit for woman with medical disorders .
Many women who have chronic diseases fall pregnant without any preconception care . This means regular discussions about pregnancy planning , the need for preconception
and preconception care . 4
MANAGEMENT OF SIMPLE MEDICAL ISSUES BEFORE PREGNANCY
THERE is a range of common medical
PRE-PREGNANCY DISORDERS THAT NEED MANAGING DURING PREGNANCY
IN the absence of preconception
practice to write this information
can be helpful for the woman and her
care and pregnancy issues should be
issues that need to be well managed
care , all women with a background
down for women and their families
partner to speak with the range of spe-
a routine component of healthcare
before pregnancy to ensure the best
medical disorder who are found to
to process . Once they have had time
cialists who may be involved in their
appointments for all women of repro-
pregnancy and neonatal outcomes .
be pregnant need pregnancy assess-
to consider written information , it
care , such as anaesthetists , obstetri-
ductive age with chronic disease .
Optimise asthma management before
ment as early as possible . A baseline
is helpful to invite them back to dis-
cians , maternal-fetal medicine special-
There is also the problem of
pregnancy ( see figure 2 ). A common
assessment is required , along with
cuss the issues again and provide the opportunity for the woman , partner
ists , psychiatrists and neonatologists . If there is a high risk of the neonate
women with high-risk medical issues who accidentally find them-
problem is the cessation of inhaled corticosteroids at the beginning of
an urgent review of all medications . Some medication doses may need to
and family to ask questions .
requiring intensive care nursery sup-
selves pregnant , leading to diffi-
pregnancy . It is important to note
be increased ( for example , thyroid
There are several other important
port , a visit to the nursery to see what
cult decisions regarding termination
that inhaled corticosteroids should
replacement therapy , antiepileptic
considerations if pregnancy is likely to
this is like in real life can assist in
of pregnancy . To avoid this , it is
be continued throughout pregnancy .
drugs ). Early appropriate manage-
be very risky . It is important to reassure
decision-making .
important to advise all women with
There are now excellent guidelines
ment needs to be started .
women that whatever they decide , or whatever happens , the very best care will be provided regardless of how risky the situation is . This helps to avoid
If pregnancy is not possible or is inadvisable
In some situations , the woman ’ s
medical issues of the risks of pregnancy , and to have an appropriate contraception plan in place . This is particularly important for women
about the management of asthma before and during pregnancy . 5
Other issues that need attention before conception include hyperten-
Careful review and follow-up
At the beginning of pregnancy ,
determine a plan regarding review
shame and secrecy around conception .
medical issues will preclude natu-
who are recovering from hormo-
sion , thyroid disease , iron deficiency
and follow-up . This requires good
If there are concerns about the risk
ral conception , and assisted fertility
nally dependent cancers ( for exam-
anaemia , gut issues that may benefit
communication between all mem-
of maternal death or serious morbid-
is contraindicated in some situa-
ple , breast cancer ), those who have
from an endoscopy or colonoscopy
bers of the pregnancy care team ,
ity , it is important to try to involve the
tions . In some circumstances , the
diseases that would be adversely
before conception , dental issues ,
including the GP .
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