self-report improved stamina, cogni- |
serology) and experiences recurrent |
early in her treatment. Attempts at |
on his work, as well as the need |
ranges. With evidence of recurrent |
tive awareness, improved pain and |
ear infections. She is treated with a |
undertaking GET result in increased |
to reduce his work hours because |
infections, Edwin starts a continu- |
temperature regulation. The off-label |
long course of clarithromycin. |
severity of symptoms. She is pro- |
of persistent symptoms of dizzi- |
ous courses of antibiotics for eight |
use of low-dose amitriptyline has also |
While her LFTs return to normal |
vided with education on pacing and |
ness, fatigue, impaired concentra- |
months. This is in addition to mel- |
garnered attention as a viable treat- |
and further blood analysis is within |
energy management and limits work |
tion, sleep disturbance, new-onset |
atonin, folic acid, vitamin B12, zinc |
ment alternative to address impaired |
the normal range, her BMI drops to |
and university commitments to two |
migraines and recurrent episodes |
and magnesium. After three years of |
cognition, fatigue and body pain. 60 However, further research and clini- |
underweight, and she continues to experience persistent and debili- |
hours a day. Over the next year, Evie gradually |
of feeling feverish. He can no longer play his chosen sport, cricket, and |
symptoms, he is diagnosed with ME / CFS. |
cal trials are required to validate the |
tating fatigue, unrefreshing sleep, |
improves, with a reduction in symp- |
reports difficulty in visiting shop- |
Twenty-five years later, Edwin |
efficacy of both LDN and low-dose |
headaches and a decline in cogni- |
tom severity. She returns to full-time |
ping centres because of increased |
continues to report relapsing – remit- |
amitriptyline. |
tive function, particularly concen- |
studies but sometimes experiences |
sensitivity to light and noise. |
ting symptoms of ME / CFS and has |
|
CASE STUDIES
Case study one
EVIE, a 20-year-old full-time university
student, has contracted EBV. Her
|
tration and memory— all of which are impacting her studies. Exertion results in limb pain, persistent nausea, dizziness and syncopal episodes. After six months of symptoms, she is |
periods of relapse.
Case study two
Edwin, a 34-year-old carpenter,
becomes ill with a suspected viral
|
Following his persistent symptoms, Edwin consults a series of doctors who offer a range of diagnoses, including vertigo and major depressive disorder. He reports adverse |
since changed careers to enable longterm periods of rest.
CONCLUSION
ME / CFS presents a complex and mul-
|
symptoms and signs include fever |
diagnosed with ME / CFS and POTS. |
infection. He self-reports experienc- |
events after taking prescribed med- |
tisystemic challenge in the absence of |
and chills, sore throat, lymphade- |
Evie is started on a regimen of |
ing a high fever lasting several days, |
ications, including antidepressants |
a diagnostic test and evidence-based |
nopathy, hepatomegaly( with ele- |
supplements, including coenzyme |
severe throat pain, and body aches |
and beta blockers. After two years, |
treatment. Its heterogeneous nature |
vated LFTs) and nausea. In the weeks |
Q10; vitamins B, C and D; and a low- |
and pain. A week later, he returns |
serology returns positive for Chla- |
— encompassing neurological, immu- |
following infection, she contracts |
dose beta blocker( for POTS). She |
to work. |
mydia pneumoniae, however, this as |
nological, gastrointestinal and other |
Mycoplasma pneumoniae( diagnosed |
receives regular vitamin B12 injec- |
Over a period of several weeks, |
the primary illness is an assumption. |
manifestations— presents an obsta- |
first with X-ray and confirmed with |
tions intramuscularly for six months |
he notices a significant impact |
Blood parameters are within normal |
cle in terms of research and the |