12 NEWS
12 NEWS
13 SEPTEMBER 2024 ausdoc . com . au
Worst antibiotic for reactions ?
|
Mohana Basu FREQUENTLY prescribed oral antibiotics can increase the risk of serious cutaneous adverse reactions in older adults almost threefold , a Canadian study suggests .
While antibiotics were a recognised cause of cutaneous adverse drug reactions ( cADRs ), University of Toronto researchers said previous studies had not compared the relative risks between antibiotic classes .
Their study found that sulfonamide or cephalosporin use in the
|
|
|
|
past 60 days was associated with a 190 % and 160 % higher risk of an ED presentation or hospital admission for cADR , respectively , compared with macrolides .
Nitrofurantoin , penicillins and fluoroquinolones were also linked to a higher risk of serious cADRs .
Macrolides were used as the comparator because they rarely caused serious cADRs , the researchers wrote in JAMA .
The most severe form of cADRs — toxic epidermal necrolysis or
|
Stevens – Johnson syndrome — has a reported mortality rate of 20-40 %.
The study used health databases from Ontario , Canada , covering 3.2 million adults aged 66 or older with outpatient antibiotic prescriptions from 2002 to 2022 .
Of these , 21,758 reported a hospital visit for cADR within 60 days of receiving outpatient antibiotics . While most attended ED only , 2852 were hospitalised , of whom 150 died in hospital .
The researchers adjusted for
|
relevant conditions , such as HIV or chronic kidney disease ; other medications ; and level of healthcare use .
They concluded that two out of every 1000 antibiotic prescriptions were associated with a hospital visit for cADR .
They also acknowledged study limitations , including the lack of a control group with no antibiotics prescribed and the reliance on ICD codes to identify cADRs .
JAMA 2024 ; 8 Aug .
|
who cares .
Contrave helps patients with obesity care less about comfort foods and break their habit of over-eating . 1 It ’ s the only oral antiobesity treatment to help them resist hunger and cravings , daily . 1-7
Visit www . contrave . com . au for more information .
Break the crave , daily 1
Prescribe Contrave in conjunction with reduced-calorie diet and increased physical activity . Treatment with Contrave should be regularly assessed . Nausea , constipation , vomiting are common side effects , particularly during the first 4 weeks of treatment . Other common side effects include decreased lymphocyte count , palpitations , tinnitus , vertigo , dry mouth , toothache , upper abdominal pain , feeling jittery , dizziness , tremor , dysgeusia , disturbance in attention , lethargy , hot flush , hyperhidrosis , pruritus , alopecia and hypertension . 1 This is not a full list , refer to the Prescribing Information for further information .
PBS Information : This product is not listed on the PBS .
Please scan the QR code to review full Product Information before prescribing . Product Information available on request from iNova Pharmaceuticals , Toll-free 1800 630 056 .
References : 1 . Contrave Product Information . 2 . Billes SK , et al . Pharmacol Res 2014 ; 84:1 – 11 . 3 . Markovic TP , et al . Obes Res Clin Pract 2022 ; 16 ( 5 ): 353 – 363 . 4 . Duromine Product Information . 5 . Saxenda Product Information . 6 . Xenical Product Information . 7 . Wegovy Product Information .
© 2024 iNova Pharmaceuticals ( Australia ) Pty Limited . ABN 13 617 871 539 . Chatswood NSW 2067 , Australia . p . 1800 630 056 . www . inovapharma . com . au Date of preparation : March 2024 . AU-2024-01-0100
Aus 4600 GPs short by 2033
Staff writer AUSTRALIA will be around 4600 GPs short of meeting patients ’ health needs by 2033 , even assuming that 90 % of GP training places are filled , suggests the government ’ s workforce analysis .
The GP Supply and Demand Study suggests that GP supply — both full-time equivalent and by headcount — is already lower than demand , based on the government ’ s estimate of Australia ’ s healthcare needs .
On headcount , the data suggest Australia is 881 GPs short in 2024 and this shortfall will rise to 2633 by 2028 and then 4557 by 2033 .
It also looks at “ unmet demand ” — the actual utilisation of GP care from patients rather than the government ’ s estimate of healthcare needs .
On this measure , the shortfall is even worse .
It predicts that Australia needs 43,300 GPs this year when it only has around 39,900 and that , by 2033 , it will need 51,300 GPs but only have 43,600 .
The report says more GPs are entering the workforce than leaving or retiring but a growing and ageing population means demand is growing much faster than supply .
The GP numbers also assume that more than 91 % of Australian General Practice Training Program places continue to be filled beyond 2025 and that more female GPs begin to work full-time .
The AMA said it had hammered home the urgency of the government supporting junior doctors to choose general practice training .
“ We need to rebuild the GP workforce , which must start with training more GPs and supporting them to work in areas of need ,” said AMA president Professor Steve Robson .
“ This requires a comprehensive policy approach that starts with medical school and expanded access to clinical placements in general practice .”
CONTR0101 AU-2024-01-0100 Aus Doc FP _ 210x273mm . indd 1 28 / 8 / 2024 9:46 PM