RECENT RESEARCH
Conclusion: Self-applied hydrotherapy and acupressure appear to be feasible and safe interventions for patients with RLS. This exploratory pilot study suggests potential benefits, though larger, welldesigned confirmatory studies are needed to validate these findings.
Clinical trial registration: This study was registered in the German Clinical Trials Register( number DRKS00029960) on August 09, 2022. https:// drks. de / search / de / trial / DRKS00029960.
Nutrition
Mann P, Jangra G, Saini K, Narwal S, Dhingra AK, Singh G. Nutraceuticals in Depression Management: Current Evidence and Perspectives. Recent Adv Food Nutr Agric. 2025 May 7. doi: 10.2174 / 012772574X361750250323 111150. Epub ahead of print. PMID: 40337958.
Results: The findings suggest that several nutraceuticals, including omega-3 fatty acids, dietary fibers, and phytochemicals, including Ashwagandha and valerian, exhibit antidepressant effects. These compounds have shown promising results in improving depressive symptoms, enhancing neuroplasticity and neurogenesis, and regulating neurotransmitter imbalances.
Conclusion: Nutraceuticals offer a novel approach to depression, providing potential benefits in alleviating depressive symptoms. Correlative review suggests that increasing intake of these substances could be an alternate method for delaying the early symptoms and course of depression. Supplementation with dietary fibers, Omega-3 fatty acids, and phytochemicals can be utilized as a complementary strategy for antidepressant therapy. mediating effect analysis showed that the chain mediating effect of frailty and depression on nutrition and quality of life in elderly stroke patients was significant, with a total indirect effect of 0.155, the mediating effect of depression as the mediating variable accounted for 54.2 % of the total indirect effect, the mediating effect of frailty as the mediating variable accounted for 25.2 % of the total indirect effect, and the chain mediating effect of frailty and depression between nutrition and quality of life of elderly stroke patients accounted for 20.6 % of the total indirect effect. It is proven that in elderly stroke patients, depression and frailty have a chain mediating effect on nutrition and quality of life. Healthcare professionals should quickly do nutritional assessments and take the necessary actions to enhance patients ' nutritional status, prevent depression and frailty, and enhance their quality of life.
Background: Depression is a common psychiatric disorder characterized by feelings of sadness, diminished interest in activities, and disruptions in sleep patterns. Pharmaco-therapy, which often involves the use of antidepressant medicines, are method for managing depression. There are potential negative effects linked to the utilization of these medicines, even though many people have found them to be beneficial.
Objective: Traditional pharmacological therapies for depression can have a variety of ad-verse effects or drawbacks. To overcome these constraints, nutraceuticals have come into the picture of interest. Nutraceuticals, which are naturally derived compounds with potential therapeutic benefits, have attracted interest as an innovative approach to treating depression. In this review, the efficacy of nutraceuticals in depression will be discussed.
Methods: To find pertinent research on nutraceuticals in the treatment of depression, a thorough literature analysis was enacted. Studies investigating the significance of nutraceuticals on depression signs, patent perspectives, and clinical studies were included.
Li X, Xue T, Zhou ZF, Jiang WB, Wei H, Li CC, Jiang YM. Chain mediating effect of frailty and depression between nutrition and quality of life in elderly stroke patients. Psychol Health Med. 2025 May 8:1-15. doi: 10.1080 / 13548506.2025.2502843. Epub ahead of print. PMID: 40338553.
Elderly stroke patients generally have a lower quality of life. This study aimed to investigate the mediating role of frailty and depression in the relationship between nutrition and quality of life in elderly stroke patients. The researcher used the convenience sampling method to select 193 cases of elderly stroke patients who were admitted to the Department of Neurology of a tertiary general hospital in Qingdao from July 2023 to March 2024, and the questionnaires were investigated using the General Information Questionnaire, the Tilburg Frailty Assessment Index Scale( TFI), the Depression Screening Scale( PHQ-9), the Simplified Quality of Life Scale for Stroke Patients( SV-SS-QoL), and the Mini-Nutrition Assessment Scale( MNA- SF). The incidence of malnutrition was 47.2 % in elderly stroke patients, whereas the quality of life score was 43.00( 40.00, 47.00), frailty was 6.00( 2.00, 8.00), and depression was 6.00( 4.00, 7.00). The
Li L, Hu L, Chen R, Yang R, Gong L, Wang J. The Particle Size of Wheat Bran Dietary Fiber Influences Its Improvement Effects on Constipation. Foods. 2025 Mar 15; 14( 6): 1001. doi: 10.3390 / foods14061001. PMID: 40338251.
Wheat bran dietary fiber( WBDF) is a potential functional additive to enrich products used for relieving constipation. The purpose of this study was to understand the effects of different particle size ranges( mean sizes of 84.14, 61.74, 37.39, and 22.33 μm) of WBDF on constipation. With the decrease in particle size, its morphology exhibited an increase in fiber fragmentation, larger pore sizes, and the formation of structural faults. The oil-holding capacity( OHC) and swelling capacity( SC) of WBDF were found to change with particle size, with the highest OHC observed at 37.39 μm and the greatest SC at 84.14 μm. Animal experiments demonstrated that the WBDF of smaller particle sizes significantly alleviated loperamide-induced constipation with an increased intestinal propulsion rate, decreased first melanin excretion time, and reduced gastric residual rate. Meanwhile, WBDF samples markedly increased serum MTL and serum AChE levels. Notably, compared with
112 | vol31 | no1 | JATMS