ATMS Journal Winter 2025 (Public Version) | Page 13

The WHO-recommended daily intake of vitamin B6 for adults is 1.3-1.7 mg per day.
Dosage range of Vitamin B6
The WHO-recommended daily intake of vitamin B6 for adults is 1.3-1.7 mg per day. 9 The various doses of vitamin B6 used in studies include 1.3 mg, 4 1.5 mg, 4 1.6 mg, 8, 14 1.7 mg, 14 2 mg, 8 5.5 mg, 4 20 mg, 44 40 mg, 31 50 mg, 30, 31, 41, 42, 45 100 mg, 4, 8, 28, 29, 31, 33, 41 150 mg, 31 200 mg, 31 300 mg, 17, 31 and 500 mg. 31
In Australia, there are regulations governing the maximum recommended daily dose of pyridoxine( from pyridoxine hydrochloride, pyridoxal 5-phosphate, pyridoxal 5-phosphate monohydrate) of an individual medicine( supplement). 46 The maximum recommended daily dosage of an individual medicine for each age group is outlined below.
• 15 mg of pyridoxine for children aged between 1 and 3 years( inclusive)
• 20 mg of pyridoxine for children aged between 4 and 8 years( inclusive)
• 30 mg of pyridoxine for children aged between 9 and 13 years( inclusive)
• 40 mg of pyridoxine for individuals aged 14 and 18 years( inclusive)
• 100 mg of pyridoxine for individuals aged 19 years and older 46
Adverse reactions of Vitamin B6
Beginning in the 1980s, several case studies documented instances of sensory neuropathy in individuals consuming high doses of pyridoxine over prolonged periods of time. 11 Neuropathy resulting from pyridoxine is marked by symmetrical and progressive deficits in the ability to perceive touch, pin-prick
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