showed a definite positive response in the general well being of the child in terms of weight gain and general activity .
3 . Muraleedharan KC , et al . Effectiveness of Homoeopathic Medicines in HIV patients - A Clinical Trial . Indian Journal of Research in Homoeopathy , 2010 , 4 , 4 , 29-35 . This study was an open-label observational prospective multi-centre design of 18 months duration . Subjects were selected from a group of people with confirmed HIV infection , who reported for homoeopathic treatment at the Outpatient Department of the Regional Research Institute of Homoeopathy , Mumbai , and the Clinical Research Unit of Homoeopathy at Chennai . The study used individualised homoeopathic medicines selected through repertorisation . The aim of the study was to observe the changes in CD4 cells and viral load volumes after the use of individualised homoeopathic medicines . A total of 72 patients who completed the follow-up period were assessed . An analysis of the results found that there was significant change in viral load volume as compared to the baseline data ( 95 % CI , 0.16 , 1.24 , p = 0.012 ), but no significant change was observed in CD4 cells ( 95 % CI , -9.31 , 57.84 , p = 0.154 ). Body Mass Index ( BMI ) ( 95 %, -1.12 , - . 57 , p < 0.001 ) showed significant improvement . After the homoeopathic intervention , WHO-QOL ( Quality of Life ) parameters showed statistically significant changes at p < 0.05 in physical health , psychological and environmental domains , but in social domain no significant change was noted .
4 . Gupta N , et al . Homoeopathic Medicinal Treatment of Autism . Indian Journal of Research in Homoeopathy , 2010 , 4 , 4 , 19-28 . An Indian research team set out to investigate the effects of individualised homeopathic treatment in autism spectrum disorders ( ASD ). A total of 25 children who had been diagnosed with ASD were enrolled in the study . They received individualised homoeopathic treatment and their progress was followed for 18 months . Significant positive and curative response with homoeopathic medicines in subjects with ASD was found , suggesting that homoeopathic medicines can provide relief from abnormal behavioural problems in children presenting with ASD .
5 . Siddiqui VA , et al . To Explore the Utility of Homoeopathic Medicine Lycopodium Clavatum in Urinary Calculi . lndian Journal of Research on Homoeopathy , 2010 , 4 , 3 , 34-38 . Workers from India ' s Central Council for Research in Homoeopathy conducted a multicentric , observational study on urolithiasis from 2005 to 2010 . A total of 90 men diagnosed with urolithiasis were enrolled in the study . The baseline symptoms score of urolithiasis was assessed before and after the treatment by using paired ' t ' test in SPSS ( Ver . 16 ). A non-parametric test of ' Wilcoxon rank sum ” was used to analyse the changes in urinary symptoms before and after the treatment . Forty-one ( 45.6 %) patients showed marked improvement , 6 ( 6.7 %) patients showed moderate improvement , 31 ( 34.4 %) patients showed mild improvement , in 11 ( 12.2 %} patients there was no significant improvement and 1 ( 1.1 %) patient did not improve . Results of this study showed the utility of Lycopodium clavatum in the dissolution of urinary calculi .
6 . Nayak C , et al . A Prospective Multicentric Observational Study to Evolve the Usefulness of the Predefined Homoeopathic Medicines in the Management of Acute Diarrheal Disease in Children . Indian Journal of Research in Homoeopathy , 2009 , 3 , 3 , 21-28 . This Indian report records the details of an observational study on acute diarrhoeal diseases in children that was undertaken with 14 pre-defined trial homoeopathic medicines to arrive at a group of medicines that may be useful for the treatment of acute childhood diarrhoea . To do this , a prospective , multi-centre observational study was conducted by the Central Council for Research in Homeopathy at its various
Institutes and Units throughout India during Oct . 2005 to Sept . 2008 . A total of 327 children aged 6 months to 12 years were enrolled and the medicines were selected on the principles of homoeopathy . Diarrhoea index scores were assessed before and after treatment using standard scoring methods . The results showed that the diarrhoea index score either deteriorated or remained unchanged from the baseline score in 1.8 % of the children treated , and improvement was seen in the remainder . The most commonly prescribed of the 14 homeopathic medicines used were Podophyllum peltatum ( n = 158 ), Chamomilla ( n = 49 ), Aethusa cynapium ( n = 25 ), Mercurius solubilis ( n = 23 ), Calcarea carbonica ( n = 21 ), Sulphur ( n = 18 ), and Phosphorus ( n = 17 ).
7 . Grover A , Bhushan B , Goel R . Double Blind Placebo Controlled Trial of Homoeopathic Medicines in the Management of Withdrawal Symptoms in Opium Addicts and its Alkaloid Derivatives-Dependents . Indian Journal of Research in Homoeopathy , 2009 , 3 , 1 , 41-44 . This research , performed at the Navjyoti Drug Demand Reduction Training Institute in New Delhi , sought to ascertain the efficacy of six pre-defined homoeopathic medicines versus placebo in the management of the withdrawal symptoms in opium addicts and its alkaloid derivatives dependents . A double-blind , randomised placebocontrolled study design was used . A total of 169 people addicted primarily to opium or its alkaloid derivatives , either natural or synthetic ( Morphine , Codeine , Heroin , Pethidine and other narcotics ) were enrolled for the study , which ran from September 2002 to August 2005 . Only male patients within 15 – 50 yrs of age attending the training institute were included in the study . Assessment of progress made in each individual symptom was recorded for both the groups . The clinical progress of each subject was recorded from the 3rd day onward after starting the treatment . An analysis of the results showed a statistically significant superiority of the
86 | vol28 | no2 | JATMS