RECENT RESEARCH
( SMD , 0.28 ; 95 % CI [ 0.02 , 0.53 ]; P = 0.03 < 0.05 ) even after a period of time after treatment .
Conclusion : MT was an effective intervention , which may have immediate effect on cancer pain and may improve physical function and global well-being . In the view of follow-up effects , MT had good effects for the reduction of pain and the recovery of physical function . However , because of limitations , the seemingly promising results should be interpreted with caution .
Lifestyle medicine
Bringmann HC , Bringmann N , Jeitler M , Brunnhuber S , Michalsen A , Sedlmeier P .
Meditation Based Lifestyle Modification ( MBLM ) in outpatients with mild to moderate depression : A mixed-methods feasibility study . Complementary Therapies in Medicine , 2021 ; 56
Background : Integrative mental health care can be applied to treat depression with a person-centered , lifestyle-modifying , and more salutogenic approach to mental health and human flourishing . In this article , we report on the feasibility and acceptability of a new mind-body program , Meditation Based Lifestyle Modification ( MBLM ), in outpatients with mild or moderate depression .
Methods : This is a single-arm mixedmethods feasibility study of n = 25 outpatients in psychiatric care . Depressive symptoms , scores for mindfulness , aspects of spirituality , and eudaemonic well-being based on yoga philosophy were assessed at baseline and at the end of the intervention . Adherence was monitored and face-to-face interviews were held after the program to explore the acceptability and feasibility of MBLM .
Results : Twenty patients ( 75 %) completed at least six sessions of the course . Adherence was 87.5 % of allocated sessions . In qualitative analysis , more than half of the participants experienced novelty and inspiration through practicing the ethical aspects of yoga ( e . g . nonviolence , truthfulness , etc .). Almost all participants experienced a decrease in emotional distress . Virtually all participants reported more self-confidence and self-acceptance . In quantitative analysis , participants reported a clinically important decrease in depressive symptoms of 39.23 % ( p = . 002 ), eudaemonic well-being increased significantly in a range of related scales and scores for mindfulness increased ( p < . 001 ).
Conclusion : MBLM is a highly acceptable and feasible program for outpatients with mild to moderate depression . This comprehensive , lifestyle-modifying approach is highly relevant to preventing and treating mental illness , and treating psychic comorbidities in patients with chronic somatic illness .
Nutrition
Vetuschi A , Battista N , Pompili S , Cappariello A , Prete R , Taticchi A , Selvaggini R , Latella G , Corsetti A , Sferra R .
The antiinflammatory and antifibrotic effect of olive phenols and Lactiplantibacillus plantarum IMC513 in dextran sodium sulfate – induced chronic colitis . Nutrition , 2022 ; 94 . https :// doi . org / 10.1016 / j . nut . 2021.111511 .
Objectives : After a chronic intestinal injury , several intestinal cells switch their phenotype to activated myofibroblasts , which in turn release an abnormal amount of extracellular matrix proteins , leading to the onset of the fibrotic process . To date , no resolutive pharmacological treatments are available , and the identification of new therapeutic approaches represents a crucial goal to achieve . The onset , maintenance , and progression of inflammatory bowel disease are related to abnormal intestinal immune responses to environmental factors , including diet and intestinal microflora components . This study aimed to evaluate the potential antiinflammatory and antifibrotic effect of a biologically debittered olive cream and its probiotic oral administration in an experimental model of dextran sodium sulfate ( DSS )– induced chronic colitis .
Methods : Chronic colitis was induced in mice by three cycles of oral administration of 2.5 % DSS ( 5 d of DSS followed by 7 d of tap water ). Mice were randomly divided into five groups : 10 control mice fed with standard diet ( SD ), 20 mice receiving SD and DSS ( SD + DSS ), 20 mice receiving an enriched diet ( ED ) with olive cream and DSS ( ED + DSS ), 20 mice receiving SD plus probiotics ( PB ; Lactiplantibacillus plantarum IMC513 ) and DSS ( SD + PB + DSS ), and 20 mice receiving ED plus PB and DSS ( ED + PB + DSS ). Clinical features and large bowel macroscopic , histologic , and immunohistochemical findings were evaluated .
Results : The simultaneous administration of ED and PB induced a significant reduction in macroscopic and microscopic colitis scores compared with the other DSS-treated groups . In addition , ED and PB led to a significant decrease in the expression of inflammatory cytokines and profibrotic molecules .
Conclusions : The concomitant oral administration of a diet enriched with biologically debittered olive cream and a specific probiotic strain ( Lactiplantibacillus plantarum IMC513 ) can exert synergistic antiinflammatory and antifibrotic action in DSS-induced chronic colitis . Further studies are needed to define the cellular and molecular mechanisms modulated by olive cream compounds and by Lactiplantibacillus plantarum IMC513 .
Zhang X , Li X , Shi H , Zhang K , Zhang Q , Tang M , Li W , Zhou F , Liu M , Cong M , Shi H .
Association of the fat-free mass index with mortality in patients with cancer : A multicenter observational study . Nutrition , 2022 ; 94 . https :// doi . org / 10.1016 / j . nut . 2021.111508
Objectives : Low fat-free mass index ( FFMI ) has been related to a higher mortality in community populations . However , information on the relationship
228 | vol27 | no4 | JATMS