randomized , pilot dose-finding study of maca root ( L . meyenii ) for the management of SSRI-induced sexual dysfunction . CNS neuroscience & therapeutics , 14 ( 3 ), 182 – 191 . https :// doi . org / 10.1111 / j . 1755- 5949.2008.00052 . x
33 . Dording , C . M ., Schettler , P . J ., Dalton , E . D ., Parkin , S . R ., Walker , R . S ., Fehling , K . B ., Fava , M ., & Mischoulon , D . ( 2015 ). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women . Evidencebased complementary and alternative medicine : eCAM , 2015 , 949036 . https :// doi . org / 10.1155 / 2015 / 949036
34 . Stojanovska , L ., Law , C ., Lai , B ., Chung , T ., Nelson , K ., Day , S ., Apostolopoulos , V ., & Haines , C . ( 2015 ). Maca reduces blood pressure and depression , in a pilot study in postmenopausal women . Climacteric : the journal of the International Menopause Society , 18 ( 1 ), 69 – 78 . https :// doi . org / 10.3109 / 13697137.2014.929649
35 . Honma , A ., Fujiwara , Y ., Takei , S ., & Kino , T . ( 2022 ). The improvement of daily fatigue in women following the intake of maca ( Lepidium meyenii ) extract containing benzyl glucosinolate . Functional Foods in Health and Disease , 12 ( 4 ), 175-187
36 . Jeon G . H . ( 2024 ). Insomnia in Postmenopausal Women : How to Approach and Treat It ?. Journal of clinical medicine , 13 ( 2 ), 428 . https :// doi . org / 10.3390 / jcm13020428
37 . Hou , J . P ., & Jin , Y . ( 2005 ) The Healing Power of Chinese Herbs and Medicinal Recipes . The Hawthorn Press Inc .: New York 38 . Shergis , J . L ., Hyde , A ., Meaklim , H .,
Varma , P ., Da Costa , C ., & Jackson , M . L . ( 2021 ). Medicinal seeds Ziziphus spinosa for insomnia : A randomized , placebocontrolled , cross-over , feasibility clinical trial . Complementary therapies in medicine , 57 , 102657 . https :// doi . org / 10.1016 / j . ctim . 2020.102657
39 . Wattanathorn , J ., Mator , L ., Muchimapura , S ., Tongun , T ., Pasuriwong , O ., Piyawatkul , N ., Yimtae , K ., Sripanidkulchai , B ., & Singkhoraard , J . ( 2008 ). Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica . Journal of ethnopharmacology , 116 ( 2 ), 325 – 332 . https :// doi . org / 10.1016 / j . jep . 2007.11.038
40 . Farhana , K . M ., Malueka , R . G ., Wibowo , S ., & Gofir , A . ( 2016 ). Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke . Evidencebased complementary and alternative medicine : eCAM , 2016 , 2795915 . https :// doi . org / 10.1155 / 2016 / 2795915
41 . Jana , U ., Sur , T . K ., Maity , L . N ., Debnath , P . K ., & Bhattacharyya , D . ( 2010 ). A clinical study on the management of generalized anxiety disorder with Centella asiatica . Nepal Medical College journal : NMCJ , 12 ( 1 ), 8 – 11 .
42 . Paocharoen V . ( 2010 ). The efficacy and side effects of oral Centella asiatica extract for wound healing promotion in diabetic wound patients . Journal of the Medical Association of Thailand = Chotmaihet thangphaet , 93 Suppl 7 , S166 – S170 .
43 . Chiaretti , M ., Fegatelli , D . A ., Ceccarelli , G ., Carru , G . A ., Pappalardo , G ., & Chiaretti , A . I . ( 2018 ). Comparison of Flavonoids and
Centella asiatica for the treatment of chronic anal fissure . A randomized clinical trial . Annali italiani di chirurgia , 89 , 330 – 336 .
44 . Chong , N . J ., & Aziz , Z . ( 2013 ). A Systematic Review of the Efficacy of Centella asiatica for Improvement of the Signs and Symptoms of Chronic Venous Insufficiency . Evidencebased complementary and alternative medicine : eCAM , 2013 , 627182 . https :// doi . org / 10.1155 / 2013 / 627182
45 . Alblooshi , S ., Taylor , M ., & Gill , N . ( 2023 ). Does menopause elevate the risk for developing depression and anxiety ? Results from a systematic review . Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists , 31 ( 2 ), 165 – 173 . https :// doi . org / 10.1177 / 10398562231165439
46 . Kamp , E ., Ashraf , M ., Musbahi , E ., & DeGiovanni , C . ( 2022 ). Menopause , skin and common dermatoses . Part 2 : skin disorders . Clinical and experimental dermatology , 47 ( 12 ), 2117 – 2122 . https :// doi . org / 10.1111 / ced . 15308
47 . Hildreth , K . L ., Ozemek , C ., Kohrt , W . M ., Blatchford , P . J ., & Moreau , K . L . ( 2018 ). Vascular dysfunction across the stages of the menopausal transition is associated with menopausal symptoms and quality of life . Menopause ( New York , N . Y .), 25 ( 9 ), 1011 – 1019 . https :// doi . org / 10.1097 / GME . 0000000000001112
48 . Park K . S . ( 2021 ). Pharmacological Effects of Centella asiatica on Skin Diseases : Evidence and Possible Mechanisms . Evidencebased complementary and alternative medicine : eCAM , 2021 , 5462633 . https :// doi . org / 10.1155 / 2021 / 5462633
JATMS | Autumn 2025 | 23