symptoms , 7 , 27-31 including hot flushes , nervousness , and interrupted sleep . Additional studies have reported statistically significant improvements in sexual function and psychological symptoms , 27 libido , 32 anti-depressant induced sexual dysfunction , 33 blood pressure , 34 and fatigue . 35
Zizyphus
Reports indicate that up to 60 % of menopausal women experience sleep disturbances or insomnia , with a significant number suffering from symptoms severe enough to impair daytime functioning . 36 Zizyphus is one of the most commonly prescribed herbs in Chinese medicine for managing insomnia and is particularly effective for night sweating . 37 In clinical trials , zizyphus extracts ( 500mg-2g ) improved sleep quality in postmenopausal women and total sleep time , sleep efficiency and sleep onset in chronic insomniacs . 38
Gotu kola
Human clinical trials support the use of gotu kola for poor memory , 39 poststroke vascular cognitive impairment , 40 anxiety , stress and depression , 41 reduced skin integrity , 42 , 43 and chronic venous insufficiency . 44 Since declining oestrogen levels are known to impact these specific health areas , 45-48 gotu kola is a well-suited herb to support the various changes that occur through the menopause transition and could be a valuable addition to a treatment plan .
Clinical summary
Phytoestrogenic and adaptogenic herbs have been the subject of scientific investigation as potential alternative therapeutics for the diverse health problems associated with fluctuating sex hormone levels that occur during the menopause transition . Given their varied mechanisms of action and extensive traditional and clinical use , hops , sage , shatavari , zizyphus , gotu kola , and maca may restore health and balance as women embark on this new phase .
REFERENCES
1 . Dadfar , F ., & Bamdad , K . ( 2019 ). The effect of Saliva officinalis extract on the menopausal symptoms in postmenopausal women : An RCT . International journal of reproductive biomedicine , 17 ( 4 ), 287 – 292 . https :// doi . org / 10.18502 / ijrm . v17i4.4555
2 . Braun , L ., & Cohen , M . ( 2014 ). Herbs and Natural Supplement : An evidence-based guide ( vol . 2 , ed . 4 ). Churchill Livingstone : Australia
3 . Štulíková , K ., Karabín , M ., Nešpor , J ., & Dostálek , P . ( 2018 ). Therapeutic Perspectives of 8-Prenylnaringenin , a Potent Phytoestrogen from Hops . Molecules ( Basel , Switzerland ), 23 ( 3 ), 660 . https :// doi . org / 10.3390 / molecules23030660
4 . Carbone , K ., & Gervasi , F . ( 2022 ). An Updated Review of the Genus Humulus : A Valuable Source of Bioactive Compounds for Health and Disease Prevention . Plants ( Basel , Switzerland ), 11 ( 24 ), 3434 . https :// doi . org / 10.3390 / plants11243434
5 . Moradi , M ., Ghavami , V ., Niazi , A ., Seraj Shirvan , F ., & Rasa , S . ( 2023 ). The Effect of Salvia Officinalis on Hot Flashes in Postmenopausal Women : A Systematic Review and Meta-Analysis . International journal of community based nursing and midwifery , 11 ( 3 ), 169 – 178 . https :// doi . org / 10.30476 / IJCBNM . 2023.97639.2198
6 . Gudise , V . S ., Dasari , M . P ., & Kuricheti , S . S . K . ( 2024 ). Efficacy and Safety of Shatavari Root Extract for the Management of Menopausal Symptoms : A Double-Blind , Multicenter , Randomized Controlled Trial . Cureus , 16 ( 4 ), e57879 . https :// doi . org / 10.7759 / cureus . 57879
7 . Meissner , H . O ., Mscisz , A ., Reich-Bilinska , H ., Kapczynski , W ., Mrozikiewicz , P ., Bobkiewicz- Kozlowska , T ., Kedzia , B ., Lowicka , A ., & Barchia , I . ( 2006 ). Hormone-Balancing Effect of Pre-Gelatinized Organic Maca ( Lepidium peruvianum Chacon ): ( II ) Physiological and Symptomatic Responses of Early- Postmenopausal Women to Standardized doses of Maca in Double Blind , Randomized , Placebo-Controlled , Multi-Centre Clinical Study . International journal of biomedical science : IJBS , 2 ( 4 ), 360 – 374 .
8 . Rodríguez Villanueva , J ., & Rodríguez Villanueva , L . ( 2017 ). Experimental and Clinical Pharmacology of Ziziphus jujuba Mills . Phytotherapy research : PTR , 31 ( 3 ),
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