ARTICLE acted as a positive control . After 6 weeks of treatment , it was shown that homeopathy and fluoxetine are effective and safe antidepressants for climacteric women . Homeopathy and fluoxetine were significantly different from placebo in response definition only . Homeopathy , but not fluoxetine , improved menopausal symptoms scored by the Greene Climacteric Scale .
5 . Saha S , et al , Documentation Of Prescriptions And Clinical Outcomes In A Homeopathic Hospital Setting In West Bengal , India . J Evid Based Complement Altern Med , 2015 , 20 , 3 , 180-185 . This work was deigned to assess prescriptions and clinical outcomes in routine homeopathic practice . Six homeopathic physicians participated in methodical data collection over a 3-month period in 6 outpatient departments of Mahesh Bhattacharyya Homeopathic Medical College and Hospital , West Bengal , India . A specifically designed Microsoft Excel spreadsheet enabled recording of consecutive appointments date , patient identity , medical condition / complaint , whether chronic / acute , new / follow-up case , patient-assessed outcome ( 7-point Likert-type scale : -3 to + 3 ), prescribed homeopathic medication , and whether other medication / s were being taken for the condition . Spreadsheets were submitted monthly for data synthesis and analysis . A total of 1972 patients ' follow-ups generated data of 2905 appointments , of which 2272 ( 78.2 %) were positive , 183 ( 6.3 %) negative , and 450 ( 15.5 %) showed no change . Strongly positive outcomes ( scores of + 2 /+ 3 ) were recorded in osteoarthritis , haemorrhoids , cough , dysfunctional uterine bleeding , chronic suppurative otitis media , and conjunctivitis .
6 . Brule D , et al . An Open-Label Pilot Study Of Homeopathic Treatment Of Attention Deficit Hyperactivity Disorder In Children And Youth . Forsch Komplementmed , 2014 , 21 . 5 . 302-309 . Researchers attempted to determine the effects of individualised homeopathic therapy for attention deficit hyperactivity disorder ( ADHD ). Participants ( aged 6-16 ) were recruited through community advertisement and outreach . Participants completed one screening and nine individualised homeopathic follow-up consultations . ADHD symptoms were assessed using the Conners 3 - Parent Questionnaire administered at each consultation . The pre- and post-study difference in Conners Global Index - Parent T-score was evaluated for each participant . Baseline data of those who showed a statistically significant improvement ( responders ) were compared to those who did not ( non-responders ). A total of 35 participants were enrolled over 11 months and 80 % completed all 10 consultations in a median of 12.1 months . There was a statistically significant improvement in 63 % of participants in the primary outcome , first occurring after a mean of 4.5 visits . Overall scores for participants completing at least two data points decreased from a baseline median of 85.5 to 74.0 ( p < 0.001 , CI 95 %). There were no significant baseline differences between responders and non-responders and no serious adverse events related to the therapy were reported .
Animal Research
1 . Bagai U , Walter NS . Antiplasmodial Potential Of Homeopathic Drugs Chelidonium And Nosode Against Plasmodium Berghei Infection . J Complement Integr Med , 2014 , 11 , 3 , 195-201 . Plasmodium berghei is associated with malaria and , in this research , the antimalarial efficacy of a combination of two homeopathic medicines , Chelidonium 30C and nosode 30C , were evaluated against Plasmodium berghei ( P . berghei ) infection in mice using Peters 4-day test . The combination of the medicines demonstrated considerable antimalarial activity with chemosuppression of 91.45 % on day 7 . The combination also significantly ( p < 0.0005 ) enhanced the mean survival time of mice which was calculated to be 22.5 ± 6.31 days , whereas it was 8.55 ± 0.83 days in infected controls .
2 . Aziz DM , Schnurrbusch U , Enbergs H . Effects Of Two Homeopathic Complexes On Bovine Sperm Mitochondrial Activity . Homeopathy , 2012 , 101 , 2 , 99-102 . Workers from Boon and Leipzig Universities evaluated the effects of two homeopathic combination products on bovine sperm mitochondrial activity . To do this , bovine sperm viability , acrosomal integrity and sperm chromatin structure were assessed in vitro before and after exposure to the homeopathic combination products . An analysis of the results showed that the homeopathic combinations stimulated the mitochondrial activity of bovine sperm without effects on their viability , acrosomal integrity or chromatin structure . The authors proposed the possibility that this translates into improved fertilisation capacity in artificial insemination and should be further investigated .
Plant Research
1 . Marotti I , et al . Transcriptome Profiling Of Wheat Seedlings Following Treatment With Ultrahigh Diluted Arsenic Trioxide . Evid Based Complement Altern Med , 2014:851263 . doi : 10.1155 / 2014 / 851263 . This Italian study , conducted by workers from the University of Bologna and others , was done to test whether 7-day-old wheat seedlings , grown from seeds , either poisoned with a sublethal dose of As2O3 ( Arsenic trioxide or Arsenicum album ) or un-poisoned , showed significant differences in gene expression profiles after the application of homeopathically prepared As2O3 compared to water ( control ). The results provided evidence for a strong gene-modulating effect of ultrahigh diluted As2O3 in seedlings grown from poisoned seeds : a massive reduction of gene expression levels to values comparable to those of the control group was observed for several functional classes of genes . A plausible hypothesis is that homeopathically prepared As2O3 treatment induced a re-equilibration of those genes that were upregulated during the oxidative stress by bringing the expression levels closer to the basal levels normally occurring in the control plants .
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