AST April 2018 Magazine AST April Magazine (3.30.18) | Page 55

FENTANYL CHEMICAL Volume 22 RELEVANCE April 2018 Edition Opioids are medically used for pain relief. One of the most common opioids is fentanyl (N-(1-(2- phenethyl)-4-piperidinyl-N- phenyl-propanamide), the effects of which are similar to heroin. Fentanyl is listed as a Sched- ule II drug under the United States Code (USC) Title 21 Controlled Substance Act and is also controlled internation- ally under Schedule I of the Single Convention on Narcot- ic Drugs of 1961. Direct syringe injection performed on GC-MS Misuse is on a significant rise due to the euphoric effect felt by the user. The ease of access has turned it into a glob- al epidemic. (Learn More as MSNBC examines the cause of the deadliest drug crisis in American history.) It is a favored painkiller because it is fast-acting. (Opioid overdose emergency department visits rose 30% in all According to the Centers for Disease Control parts of the U.S. from July 2016 through September 2017.) and Prevention (CDC), fentanyl is up to 100 times more potent than morphine and many Because of its high potency and the fact that users don’t know how much to administer, fentanyl has led to a sig- times that of heroin. nificant surge in overdose deaths. In the 1980s, fentanyl became infamous as a street drug. By the 2000s, drug dealers began adding fentanyl to her- According to the CDC, “Overdose deaths involving syn- oin to create an even more intense high that onsets very thetic opioids other than methadone, which includes quickly. fentanyl, increased by 72% from 2014 to 2015. 53