ASH Clinical News October 2016 | Page 42

Public Access Open-Access Glossary Open Access (OA): Making peer-reviewed scholarly manuscripts freely available online, permitting any user to read, download, copy, distribute, print, search, or link to the full text of these articles, crawl them for indexing, pass them as data to software, or use them for any lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. Open Educational Resources (OER): Openly licensed, online educational materials for sharing, use, and reuse. Copyleft: A form of licensing that makes a creative work freely available to be modified and requires all modified and extended versions of the creative work to be free, as well. (OA does not require works to be copyleft, nor does it necessarily exclude copyleft works from being OA.) Creative Commons (CC): A suite of licenses that set out the rights of authors and users as alternative to the standard copyright. CC Attribution (CC-BY): A license clause that allows the reuse, sharing, and remixing of materials providing the original author is appropriately attributed. CC Non Commercial (CC-NC): A license clause allowing the reuse, sharing, and remixing of materials providing that it is for non-commercial purposes. CC No Derivatives (CC-ND): A license clause requiring that derivatives are not made of the original works. CC Share Alike (CC-SA): A license clause requiring that derivative works have the same license as the original. CC-O: A waiver of copyright with no rights reserved. Paywall: A restriction via a financial barrier to research. Login wall: A requirement to log in to a system in order to access content. Open-washing: The appearance of OA for marketing purposes, while continuing proprietary practices. Green OA: Making a version of a manuscript freely available in a repository. Gold OA: Making the final version of a manuscript freely available on publication. Diamond OA: A form of gold OA where there is no APC. Gratis OA: A work is available to read free of charge, though reuse is restricted. Libre OA: A work available under an open license. Version of Record (VOR): The final version of a manuscript after peer review and publisher processing. 40 ASH Clinical News for the OA designation is that the research have a critical impact on patient care, Dr. Löwenberg, who also is professor of hematology at Erasmus University Medical Center in Rotterdam, the Netherlands, explained. The open designation is entirely up to the discretion of the Blood editors. “Basically, we make any clinical trial or any research that has clinical significance open access.” Other publishing models grant OA status after a certain period of time. For instance, NEJM makes all research articles OA six months after publication, though not copyright release, while the Journal of the American Medical Association makes research articles freely available after six months for the main journal and after a year for its specialty journals. Cheers for Peer Review? Dr. Löwenberg pointed out that free access does not mean a “free-for-all” when it comes to crosschecking the research – all Blood articles undergo the same peer-review process “We have a high-quality journal, so what we publish should be of broad interest, should have an impact on the field, and, perhaps most importantly, should be right. That requires a sophisticated peer-review system,” Dr. Löwenberg said. Usually, three experts will review the manuscript and, if they green light it as particularly important, the paper goes back to the authors to address any reviewer queries with an eye toward making the paper even better, he explained. The average time to “First Decision” for all papers is around 19 days, according to the Blood website. While Dr. Löwenberg said he appreciates that the OA movement is leveling the playing field when it comes to making information publicly available, he questioned whether those papers offer as much scientific value as those published traditionally – particularly if they don’t undergo peer review. “I feel like every day, a new journal is founded, but I wonder, ‘Who is interested in the content of those journals?’” he said. “I worry that they contain a lot of junk science. I believe a reader wants to be assured that, when he or she opens a particular journal, it contains high-quality, peer-reviewed information. This information is considered ‘right,’ or, in other words, truthful and reproducible.” Peer review is important, Dr. MacCallum agreed, but it’s not without its own problems, such as reviewer bias (based on gender, geography, practice-level, or other factors) or a failure to fully declare competing interests. “It is widely accepted that peer review is not perfect,” she said. “I was a professional editor for 18 years, and I handled thousands of manuscripts – I’ve seen the best and worst of peer review.” As science grows more complex, Dr. MacCallum suggested that the model of one editor and a couple of reviewers looking at a manuscript may no longer be adequate. “Science is becoming increasingly global, collaborative, and multidisciplinary with huge datasets – how can one or two reviewers really assess every aspect of a paper?” Even with those processes in place, those models are still based on an old algorithm; a more appropriate paradigm would be open peer review, Dr. MacCallum offered. In this model, reviewer information would be transparent and other interested parties who are not formal reviewers could still offer comments. The review process would continue after publication to ensure the ongoing accuracy of the data. “OA is about the infrastructure to support digitally linking research objects in a networked, global, interactive environment,” Dr. MacCallum said. “The responsibility of OA publishers is to facilitate and enable that infrastructure through commonly agreed-upon standards to provide the tools and infrastructure to enable others to share research freely. It’s not just about slapping the article up on the web.” The Preprint Pathway In the fields of physical sciences and mathematics, “preprint”’ has been in play for some time. In this model, researchers upload their articles to a preprint server (the site where the content is hosted); that work can then be accessed – and commented upon – by end-users. While the formal structure of preprint may be relatively new, the concept of sharing one’s work with colleagues is not, Jessica Polka, PhD, director of ASAPBio in Cambridge, Massachusetts, pointed out. “I think that scientists have been sharing their work before publication in various ways – face-to-face meetings, a poster presentation, a talk at a seminar. Preprint is bringing that kind of sharing on to the internet and democratizing the access to that content.” ASAPBio is a researcher-driven initiative to promote preprints. However, unlike arXiv.org or “I feel like every day, a new journal is founded, but I wonder, ‘Who is interested in the content of those journals?’ ... I worry that they contain a lot of junk science.” —BOB LÖWENBERG, MD, PhD bioRxiv.org – two major preprint servers in the physical sciences realm – ASAPBio does not have a preprint server. Rather, it’s an advocacy organization for the preprint movement, Dr. Polka explained. What are the benefits of preprint and how does it differ from OA? First, preprint is an opportunity for researchers to get feedback on their work without going through the formal submission process to a journal – OA or otherwise. “In one sense, preprint is OA, in that there are typically no restrictions on viewing or reading the content,” Dr. Polka noted. “But one advantage that preprint offers over OA is that the work gets out October 2016