ASH Clinical News October 2016 | Page 17

CLINICAL NEWS Waging a War on the Wage Gap Global Cancer Drug Prices: Who Pays What and Where? Female doctors are paid nearly 10 percent less than their male counterparts, regardless of experience, specialty, and other factors, according to an analysis published in JAMA Internal Medicine. Using annual salary information from 10,241 academic physicians (6,692 men and 3,549 women) at 24 public medical schools, the researchers found a gap between male and female doctors: $257,957 for men and $206,641 for women, for an absolute difference of $51,315. $257,957 It’s no secret that the United States has higher cancer drug prices than other countries, but the magnitude of these differences reported in an analysis of global cancer drug prices may hold a few surprises. These differences persisted even after adjustment for age, experience, faculty rank, specialty, total publications, and clinical revenue: $247,661 for men and $227,783 for women, for an absolute difference of $19,878. Researchers analyzed the price of monthly drug doses for 23 cancer drugs (15 of which are available generically) across six countries (Australia, China, India, South Africa, the United Kingdom, and the United States). $247,661 They found U.S. drug prices were higher, for both brandname and generic drugs. $227,783 $206,641 $300,000 10,000 800 700 $250,000 8,000 600 500 6,000 $200,000 400 4,000 300 200 2,000 $150,000 100 0 $100,000 HIGHEST United States ($8,694) LOWEST India ($1,515) 0 HIGHEST United States ($654) LOWEST South Africa ($120) Though the United States paid the most for cancer drugs, these drugs were considered more affordable, based on gross domestic product per capita (GDPcap). In the United States, the average monthly price of cancer drugs amounted to 192% of GDPcap, compared with 313% of GDPcap in India. $50,000 $0 Source: Jena AB, Olenski AR, Blumenthal DM. Sex differences in physician salary in US public medical schools. JAMA Intern Med. 2016 July 11. [Epub ahead of print] Growing by Leaps and Bounds Compared with their counterparts from 60 years ago, children who survive cancer are living much longer, healthier lives, according to a U.K. study. Study authors reviewed data for 34,489 survivors of childhood cancer who were diagnosed between 1940 and 2006. Source: Goldstein DA, Clark J, Tu Y, et al. Global differences in cancer drug prices: A comparative analysis. J Clin Oncol. 2016;34(suppl):LBA6500. 70% 70% (beyond what would be expected in the general population) from recurrence or progression of original cancer fewer excess deaths fewer deaths Comparing patients treated after 1990 versus before 1970, the younger population had: Survivors in the younger group also had fewer health problems. For example, the rate of excess deaths attributable to circulatory issues was 22% in survivors 50-59 years and 37% in survivors ≥60 years. ASHClinicalNews.org Better treatments and better monitoring are to thank for this increase in survivorship, the authors of the study noted, with improvements aligning with the developments of chemotherapy and bone marrow transplants. Source: Fidler MM, Reulen RC, Winter DL, et al. Long term cause specific mortality among 34 489 five year survivors of childhood cancer in Great Britain: population based cohort study. BMJ. 2016 July 29. [Epub ahead of print] ASH Clinical News 15