CLINICAL NEWS
TABLE 2.
Incidence Rates of Avascular Necroses
Incidence of AVN
p Value
Gender
Male
0.8%
Female
1.2%
0.19
Age
>10 years
4.3%
≤10 years
0.8%
0.001
Body mass index at beginning of treatment
High
3.1%
Normal
1.6%
Low
0.3%
0.0001
for all
Response to treatment on day 15
>10% blast cells in the bone marrow
1.8%
≤10% blast cells in the bone marrow
0.9%
0.057
changes in AVN: 2,000 mg/m2 methotrexate was as ͽ