ACTIVE IS running on the boardwalk in the morning, a couple of laps
in the pool this afternoon, and Ultimate Frisbee® with friends on Saturday
Indication for XYNTHA
XYNTHA® Antihemophilic Factor (Recombinant) is indicated in adults and children with hemophilia A (congenital
factor VIII deficiency or classic hemophilia) for control and prevention of bleeding episodes and for perioperative
management.
XYNTHA does not contain von Willebrand factor and, therefore, is not indicated in von Willebrand’s disease.
Important Safety Information for XYNTHA
• Do not use in patients who have manifested life-threatening immediate hypersensitivity reactions, including
anaphylaxis, to the product or its components, including hamster proteins.
• Allergic-type hypersensitivity reactions, including anaphylaxis, are possible with XYNTHA. Inform patients of the
early signs or symptoms of hypersensitivity reactions (including hives, generalized urticaria, chest tightness,
wheezing, and hypotension) and anaphylaxis. Discontinue XYNTHA if hypersensitivity symptoms occur and
administer appropriate emergency treatment. XYNTHA contains trace amounts of hamster proteins. Patients
may develop hypersensitivity to these proteins.
• Inhibitors have been reported following administration of XYNTHA. Monitor patients for the development of
factor VIII inhibitors by appropriate clinical observations and laboratory tests.