ASH Clinical News December 2016 | Page 68

Literature Scan Rates of red blood cell (RBC) transfusion were similar for patients receiving FFP compared with patients who received PCC, according to the results of four studies that reported on this endpoint: 27.1 percent (n=100/369) versus 24.6 percent (n=93/378; OR=0.88; 95% CI 0.531.43; p=0.6). In two secondary safety outcomes that were also measured, PCC was associated with a lower incidence of post-transfusion congestive heart failure or volume overload (OR=0.27; 95% CI 0.13-0.58; p<0.001), but not a significant reduction in thro