ASH Clinical News December 2014 | Page 73

When bleeds happen, NovoSeven® RT provides your patients with: 2-5 5 minutes hours Rapid reconstitution1 Rapid administration1 Rapid bleed control3 16ϫ less infusion volume than pd-aPCC1,4,b Up to 18ϫ faster to infuse than pd-aPCC1,4,b,c Helps control joint bleeds in as few as 5 hoursd,e Products scaled proportionally from actual size. Ask your local Novo Nordisk Representative for a free NovoSeven® RT Patient Starter Kit Find your Rep at NovoSevenRT.com/hcp Important Safety Information (cont’d) Warnings and Precautions (cont’d) • Exercise caution when administering NovoSeven® RT to patients with an increased risk of thromboembolic complications, such as those with disseminated intravascular coagulation (DIC), advanced atherosclerotic disease, crush Print-only content injury, septicemia, uncontrolled post-partum hemorrhage, history of coronary heart disease, liver disease, post-operative immobilization, in elderly patients, in neonates, or in patients receiving concomitant treatment with aPCCs/PCCs (activated or nonactivated prothrombin complex concentrates). • Hypersensitivity reactions, including anaphylaxis, have been reported with NovoSeven® RT. Administer only if clearly needed in patients with known hypersensitivity to NovoSeven® RT, any of its components, or mouse, hamster, or bovine proteins. Should symptoms occur, discontinue NovoSeven® RT and administer appropriate treatment. • Factor VII deficient patients should be monitored for prothrombin time (PT) and factor VII coagulant activity (FVII:C). If FVII:C fails to reach the expected level, or PT is not corrected, or bleeding is not controlled after treatment with the recommended doses, anti