ASH Clinical News Advances in Hematology Research & Patient Care: Hi | Page 3

JANUARY 2016 AMERICAN SOCIETY OF HEMATOLOGY HEADQUARTERS 2021 L Street NW, Suite 900 Washington, DC 20036 www.hematology.org Tel: 202-776-0544 EDITOR-IN-CHIEF Mikkael Sekeres, MD, MS Vice-Chair for Clinical Research Director, Leukemia Program Cleveland Clinic, Taussig Cancer Institute Cleveland, OH ASSOCIATE EDITORS Beth Faiman, CNP, PhD Cleveland Clinic Cleveland, OH Alice Ma, MD University of North Carolina School of Medicine Chapel Hill, NC CONTENTS David Steensma, MD Dana-Farber Cancer Institute Boston, MA Keith Stewart, MBChB, MBA Mayo Clinic Scottsdale, AZ INTERVIEWS 6 7 Dr. Rodgers on the future directions and challenges in treating sickle cell disease. PUBLISHER American Medical Communications EDITORIAL Griffin Rodgers, MD Jill Johnsen, MD Dr. Johnsen shares her insight into translating genetic information into caring for hematologic patients. CLINICAL NEWS MANAGING EDITORS Ariel Jones-DeMaio, AMC Karen Learner, ASH 12 GBT440: A New Option for Patients with Sickle Cell Disease 16 New Options for Older Patients with Hodgkin Lymphoma ASSOCIATE MANAGING EDITOR Kerri Fitzgerald, AMC 13 N-Acetylcysteine Increases Platelet Counts in TTP 17 Over-Reporting of At-Home Chemotherapy Adherence Using Self-Reporting Methods 13 Pracinostat Added to Azacitidine in MDS: No Clinical Benefit, But Added Toxicity 18 Patient-Centered Outcomes One Year After Pulmonary Embolism DIGITAL PROJECTS MANAGER Chris Gedikli 14 Eltrombopag in Patients with Lower-Risk MDS and Thrombocytopenia 19 ADVERTISING 15 ART DIRECTOR Ari Mihos ASSISTANT ART DIRECTOR Charlene DePrizio ACCOUNT MANAGER Nick Luciano [email protected] Gene Conselyea [email protected] Recruitment advertising orders can be sent to: DIRECTOR, RECRUITMENT CLASSIFIEDS Lauren Morgan [email protected] ©2016 by the American Society of Hematology. All materials contained in this newsletter are protected by copyright laws and may not be used, reproduced, or otherwise exploited in any manner without the express prior written permission of ASH Clinical News. Any third-party materials communicated to ASH Clinical News become its copyrighted property and may be used, reproduced, or otherwise exploited by ASH Clinical News. PET-Guided Chemotherapy De-Escalation in Hodgkin Lymphoma Predicting Osteonecrosis in Children with ALL 20 Ibrutinib Safe, Effective in Older Patients with CLL/SLL 21 Lumiere: Alisertib in Relapsed/Refractory PTCL All correspondence for the American Society of Hematology should be sent to: American Society of Hematology, 2021 L Street NW, Suite 900, Washington DC 20036. Neither the American Society of Hematology nor the publisher is responsible for statements made by any editor or contributor. Statements, editorials, or opinions expressed in ASH Clinical News magazine do not necessarily represent official policy of the American Society of Hematology unless so stated. No responsibility is assumed by the American Society of Hematology or the Publisher for any injury or damage to persons or property as a matter of product liability, negligence or otherwise or from any use or operation of any methods, products, instructions or ideas contained in the material herein.  Although all advertising material published in ASH Clinical News magazine is expected to conform to ethical (medical) standards, inclusion in this publication does not constitute a guarantee or endorsement by the American Society of Hematology or the Publisher of the quality or value of such product or of the claim made of it by its manufacturer. About the American Society of Hematology The American Society of Hematology (ASH) is the world’s largest professional society concerned with the causes and treatments of blood disorders. The mission of the Society is to further the understanding, diagnosis, treatment, and prevention of disorders affecting the blood, bone marrow, and the immunologic, hemostatic and vascular systems, by promoting research, clinical care, education, training, and advocacy in hematology.