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CLINICAL NEWS Data Stream 15% 12.6% 12.5% 12% 12.7% 12.2% 9% 6% Hematologists Under the Influence? 3% 0% Flexible-hour Group Standard Group After 4 Years A cancer doctor who accepts fees from a pharmaceutical manufacturer is more likely to prescribe a medicine from that company, according to a review published in The Oncologist that finds that these types of payments can sway specialists’ prescribing patterns. Reviewing data from the Centers for Medicare and Medicaid Services Open Payments System and Medicare Part D program between 2013 and 2015, researchers found that hematologists/oncologists who received any industry payments related to a chronic myeloid leukemia drug were Doc Around the Clock Despite concerns about how medical trainees’ demanding work hours can affect their ability to care for patients, longer shifts do not jeopardize patient safety, according to a New England Journal of Medicine report. In a randomized noninferiority trial, authors assigned internal-medicine residency programs to abide standard 16-hour shifts or use flexible duty-hour rules that did not specify limits on shift length or mandatory time off between shifts. After 4 years, the changes in 30-day mortality for patients from baseline were minimal with either shift schedule: 12.6% to 12.5% in the flexible-hour group vs. 12.7% to 12.2% in the standard group (p=0.03). “Patients cared for by residents on longer shifts did just as well,” lead author David Asch, MD, MBA, said. Although people might expect residents on short shifts to be more alert and do a better job, “there are other competing issues [like ‘passing off of care’]. It’s not just, ‘Is your doctor tired?’” 22% more likely to prescribe that company’s drug than doctors who did not receive payments. This association was strongest for physicians who consistently received travel and consulting payments throughout the year and for physicians who received larger payments. Source: Mitchell AP, Winn AN, Lund JL, Dusetzina SB. Evaluating the strength of the association between industry payments and prescribing practices in oncology. Oncologist. 2019 February 6. [Epub ahead of print] Drug Shortages in 2018 306 Source: Silber JH, Bellini LM, Shea JA, et al. Patient safety outcomes under flexible and standard resident duty-hour rules. N Engl J Med. 2019;380:905-14. I Want an Old Drug Following a 3-year stretch of decline, drug shortages are making a comeback. In 2018, there were 306 products on the U.S. Food and Drug Administration Drug Shortages list, including 186 new products added that year. That number was up from 146 new products added in 2017, and is the highest numbers since 2012, when 204 drugs were added. Many of the products in short supply were basic medicines like sterile surgical fluids and injectable opioids. Source: American Society of Health-System Pharmacists Drug Shortages Statistics, 2019. ASHClinicalNews.org 186 new products added in 2018 ASH Clinical News 25