In hemophilia B
TAKE CONTROL
TO A
HIGH
LEVEL
WITH REBINYN ®
Clayton, 34 years old, is a pilot who hikes and camps
in his spare time. Clayton lives with hemophilia B.
Image of hemophilia B patient shown is for illustrative purposes only.
INDICATIONS AND USAGE
Rebinyn ® , Coagulation Factor IX (Recombinant),
GlycoPEGylated, is a recombinant DNA derived
coagulation Factor IX concentrate indicated for
use in adults and children with hemophilia B for
on demand treatment and control of bleeding
episodes and perioperative management of
bleeding.
Limitations of Use: Rebinyn ® is not indicated for
routine prophylaxis or for immune tolerance
induction in patients with hemophilia B.
IMPORTANT SAFETY INFORMATION
Contraindications
• Rebinyn ® is contraindicated in patients with a
known hypersensitivity to Rebinyn ® or its
components, including hamster proteins.
Warnings and Precautions
• Hypersensitivity reactions, including
anaphylaxis, may occur. Signs may include
angioedema, chest tightness, difficulty
breathing, wheezing, urticaria, and itching.
Discontinue Rebinyn ® if allergic or
anaphylactic-type reactions occur and initiate
appropriate treatment.
• Development of neutralizing antibodies
(inhibitors) to Factor IX may occur. Monitor
patients for development of factor IX
inhibitors if bleeding is not controlled with the
recommended dose of Rebinyn ® or if expected
Factor IX activity plasma levels are not
attained. Factor IX activity assay results may
vary with the type of activated partial
thromboplastin time reagent used.