OCTOBER 2018
AMERICAN SOCIETY OF HEMATOLOGY HEADQUARTERS 2021 L Street NW , Suite 900 Washington , DC 20036 www . hematology . org Tel : 202-776-0544
EDITOR-IN-CHIEF Mikkael Sekeres , MD , MS
Vice-Chair for Clinical Research Director , Leukemia Program Cleveland Clinic , Taussig Cancer Institute Cleveland , OH
ASSOCIATE EDITORS Beth Faiman , CNP , PhD
Cleveland Clinic Cleveland , OH
Alice Ma , MD University of North Carolina School of Medicine Chapel Hill , NC
David Steensma , MD Dana-Farber Cancer Institute Boston , MA
Keith Stewart , MBChB , MBA Mayo Clinic Scottsdale , AZ
PUBLISHER American Medical Communications
EDITORIAL
MANAGING EDITORS Kristin Hubing , ASH Ariel Jones-DeMaio , AMC
ASSOCIATE MANAGING EDITOR Kerri Fitzgerald , AMC
EDITORIAL ASSOCIATE Laurie Adamson , ASH
ART DIRECTOR Ari Mihos
ASSISTANT ART DIRECTOR Charlene DePrizio
DIGITAL PROJECTS MANAGER Chris Gedikli
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Sima Sherman ssherman @ americanmedicalcomm . com
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© 2018 by the American Society of Hematology . All materials contained in this newsletter are protected by copyright laws and may not be used , reproduced , or otherwise exploited in any manner without the express prior written permission of ASH Clinical News . Any third-party materials communicated to ASH Clinical News become its copyrighted property and may be used , reproduced , or otherwise exploited by ASH Clinical News .
CONTENTS
HOW I TEACH
Alice Ma ' s tips and tricks for teaching the coagulation cascade 4
PRACTICE UPDATE
A look at ASH ' s guidelines efforts for venous thromboembolism and von Willebrand disease 5
DRAWING FIRST BLOOD
Ralph V . Boccia , MD , and Michael Auerbach , MD , on the optimal iron formulation for treating pregnant women with iron deficiency 6
MEETING NEWS
Updates in classical hematology from recent medical meetings 9
FEATURE
Breakthroughs in Gene Therapy for Hemophilia The Race to a ” Cure ” for Hemophilia 16
IN THE LITERATURE
Gene Therapy Reduces Transfusion Need in Beta-Thalassemia 19
Tumor Site , D-Dimer Markers Predict VTE Risk in Cancer 20
All correspondence for the American Society of Hematology should be sent to : American Society of Hematology , 2021 L Street NW , Suite 900 , Washington DC 20036 .
Neither the American Society of Hematology nor the publisher is responsible for statements made by any editor or contributor . Statements , editorials , or opinions expressed in ASH Clinical News magazine do not necessarily represent official policy of the American Society of Hematology unless so stated . No responsibility is assumed by the American Society of Hematology or the Publisher for any injury or damage to persons or property as a matter of product liability , negligence or otherwise or from any use or operation of any methods , products , instructions or ideas contained in the material herein .
Although all advertising material published in ASH Clinical News magazine is expected to conform to ethical ( medical ) standards , inclusion in this publication does not constitute a guarantee or endorsement by the American Society of Hematology or the Publisher of the quality or value of such product or of the claim made of it by its manufacturer .
About the American Society of Hematology The American Society of Hematology ( ASH ) is the world ’ s largest professional society concerned with the causes and treatments of blood disorders . The mission of the Society is to further the understanding , diagnosis , treatment , and prevention of disorders affecting the blood , bone marrow , and the immunologic , hemostatic and vascular systems , by promoting research , clinical care , education , training , and advocacy in hematology .
2 Focus on Classical Hematology