Grande released her second studio album My Everything on August 25, 2014, and debuted atop the Billboard 200.[80] Its lead single "Problem" features Australian rapper Iggy Azalea and premiered at the 2014 Radio Disney Music Awards on April 27.[81][82] The song debuted at number three (eventually climbing to number two) on the Billboard Hot 100, and debuted at number one on the UK Singles Chart, becoming Grande's first number one single in the United Kingdom.[83] The album's second single, "Break Free", featuring German musician and producer Zedd,[84] peaked at number four in the United States.[85] She performed the song as the opening of the 2014 MTV Video Music Awards and won Best Pop Video for "Problem".[86] Grande and Nicki Minaj provided guest vocals on "Bang Bang", the lead single from Jessie J's album Sweet Talker,[87] which peaked at number one in the UK and reached number three in the US.[85] With the singles "Problem", "Break Free", and "Bang Bang", Grande joined Adele as the only female artist with three top ten singles simultaneously on the Billboard Hot 100 as a lead artist.[85]
Grande was the musical performer on Saturday Night Live, with Chris Pratt as the host on September 27, 2014.[88] That same month, the third single from My Everything, "Love Me Harder", featuring Canadian recording artist The Weeknd, was released and peaked at number seven in the United States.[89] The song became her fourth top ten single of 2014, the most by any artist that year.[90] In November 2014, Grande was featured in Major Lazer's song "All My Love" from the soundtrack album for the film The Hunger Games: Mockingjay – Part 1.[91] The same month, Grande released a Christmas song titled "Santa Tell Me" from her Christmas EP, Christmas Kisses.[92] She later released the fifth and final single from My Everything, "One Last Time", which peaked at number 13 in the US.[93]
In February 2015, Grande embarked on The Honeymoon Tour, with shows in North America, Europe, Asia and South America.[94] Grande was featured on Cashmere Cat's song "Adore", which was released in March 2015.[95] In the spring, she signed an exclusive publishing contract with Universal Music Publishing Group covering her entire catalogue.[96] Grande also filmed an episode for the Fox television reality series Knock Knock Live,[97] but the show was cancelled before her episode aired,[98] and guest-starred on several episodes of the Fox comedy-horror television series Scream Queens as Sonya Herfmann/Chanel#2 from September to November 2015.[99][100] She recorded the duet "E Più Ti Penso" with Italian recording artist Andrea Bocelli, which was released in October 2015 as the lead single from his album Cinema,[101] and covered the song "Zero to Hero" from the film Hercules for the compilation album We Love Disney.[102] Grande also released her second Christmas EP, Christmas & Chill in December 2015.[103]