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GETTING SMELLY FOR SCIENCE Although self-experimentation was not unique for this era, Leeuwenhoek is especially remembered for his peculiar and sometimes smelly home-based experiments. GrUbBy lIcE LeGs To observe and describe a louse feeding, Leeuwenhoek let a louse sit on his hand and draw blood from him so he could observe how it fed. Super, super gross. Ed. In 1683, Leeuwenhoek made observations about plaque on teeth. He didn’t clean his teeth for three days and then collected his own plaque for observations. He also continued his observations by collecting plaque from two women and two men who had never cleaned their teeth before. (Super gross. Ed.) He looked at all of the specimens under his microscope and wrote about each one. He described the plaque of one of the men by saying: ‘an unbelievably great company of living animalcules, a-swimming more nimbly than any I had ever seen up to this time’ If you think that is disturbing then you may not want to read on... Leeuwenhoek conducted another lice experiment in which he put adult lice on his leg and covered them with his stocking then left that stocking on and didn’t have a wash for six days. After six days he removed his sock and observed over 80 louse eggs stuck to his leg hair. But it doesn’t stop here, brace yourself for feeling itchy... Leeuwenhoek then put the sock back on and left it on for another four days with no washing (I make that a total of ten days without a wash...) . The result was that he had at least 25 young lice living on his leg. At the end of the experiment he felt so disgusted by it all that he threw his lice-filled sock out of the window and then cleaned his leg by rubbing it with ice two times. (Bath? soap? Maybe he should be called Peew-enhoek? Ed.) Based on his findings he calculated that in just eight weeks, two lice could become ten thousand young lice on a ‘Person, who does not have a change of linen or garments.’ The sketches in his notebook of ‘animalcules’ in the mouth are described today as microorganisms. The ones he saw specifically include oral bacteria. This finding was the gateway to the amazingly complex world that exists within the human mouth. SwEaT CoLlEcToR Leeuwenhoek also designed an experiment to find out how much water is regularly lost through the skin in a day. To do this he weighed a dry beaker then put his own hand inside it and used a handkerchief to seal the top of the glass. He watched moisture condense on the inside of the glass. Finally he was able to weigh the sweat he had collected from himself and, based on the surface area of his hand, he calculated how much vapour was excreted. From this he estimated that the whole body must produce 28 fluid ounces (828 ml) every 24 hours. A few of Leeuwenhoek’s other peculiar experiments: ● When he was ill he examined his own tongue and saw it had a furry texture. He scraped the white substance off his tongue and looked at it under the microscope for observation. ● He examined pepper water, river water, snow water, rain water, dirty water from a well near his house and sea water collected for him by a stranger. Often leaving it out a number of days and examining it regularly. ● He also observed cheese fungi, animal sperm, animal bile liquid, urine and exploding gun powder. (Super super super gross. Ed.) Cathro TeEtH ScRaPiNg