AQHA Magazine July August 2019 AQHA July-Aug 2019 Final | Page 27
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imbalances and vitamin deficiencies. Electrolytes (sodium,
potassium, magnesium and calcium) are crucial for
proper muscle function, and must be provided especially
when a horse is sweating excessively and working hard.
Supplementation with L-carnitine or acetyl-L-carnitine
has also been shown to reduce the excessive muscle
glucose storage. Adding vitamin E (up to 5000IU/day)
increases the muscle membrane integrity and has been
shown to decrease muscle enzyme leakage out of the
cells. It can also prevent post-exercise elevation in muscle
enzymes and clinical episodes of tying up within 3 to 6
months. Improvement in attitude, stride, energy, exercise
tolerance, and muscling are also noted by most owners.
Dietary alterations must be combined with regular
exercise, minimizing stress and regular routines. Access
to a paddock is really beneficial for gentle exercise,
but because we want to keep starch/sugar intake low,
pasture should be equivalent to what you would use
for a horse prone to laminitis. The return to exercise
should be very gradual – initially just a few minutes of
uncollected walk on the lunge or in a round yard (horse
walkers are not recommended). If ridden, the ride should
be short and small circles and steep hills avoided. Over 3
weeks, uncollected walking and trotting can be gradually
increased to 30 minutes a day. Quarter horses with PSSM
may have elevated blood CK levels for 4–6 weeks as their
exercise increases and once fit, regular daily exercise must
be maintained.
Hand walking can worsen the condition and should be
short (5-10 minutes) and slow, and preceded by free
paddock or arena exercise. Exercise should be increased
by a few minutes every few days. Once horses are capable
of trotting for 30 minutes on the lunge without difficulty,
work under saddle can begin. Horses should be in a small,
quiet paddock for most of the day. Once horses are on
a regular exercise schedule and the diet is adjusted,
improvement can occur within 1 week, while in others it
may take weeks to months and a prolonged spell or even
a permanent paddock may be required.
Figure 1.
Figure 1. A normal biopsy (top) and a biopsy from a horse
with PSSM (bottom). The darker areas in the PSSM biopsy
indicate the accumulation of excess abnormal glycogen.
In the middle of last century we thought that all tying-up
was due to lactic acid. But late last century, and despite
some internet sites failing to realise this, we found that
lactic acid has nothing to do with tying-up. There is no
single procedure or set of procedures that guarantee
against further episodes of the ERS. However, appropriate
management helps to reduce the likelihood or frequency
of future episodes. The most basic aim of equine veterinary
clinical nutrition is to design diets that help manage or
prevent diseases. Recently equine veterinarians have
applied nutrigenomics where nutritional requirements
are matched to the horse’s individual genetic make-up.
Knowing exactly what form of ER a horse has makes
management considerably easier.
This article is intended to help you understand more about tying-up, as well as the causes, diagnostic, and management of the condition.
This information is not a substitute for veterinary care; if you suspect any problem with your horse you should
IMMEDIATELY contact your veterinarian.©J Stewart 2019
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JULY/AUGUST ISSUE 2019