Supernatural is the story of a pair of brothers who are highly dependant of one another. They're lives are filled to the brim with depression and ild psychosis. Mild, that is, until season 7. In seson 7, Sam develops schizonphrenic like symptoms because of the time he spent in Hell. About half way through the season, Sam is put in a mental hospital due to his sleep deprivation, caused by his hallucinations of Lucifer. Dean suffers from severe depression, his best friend betrayed him and then when he was trying to make things right, he died. On top of his best friend's death, Dean is also struggling with the death of his father-like figure.