Antibody Fragments Market Research Report and Forecast up to 2024 Antibody Fragments Market | Page 2

Asia Pacific
Latin America
Middle East Africa
Firstly, antibody fragments are segmented into F(ab) fragment and F(ab’)2. A
papain digestion of an antibody will yield two F(ab) fragments. F(ab) fragment is a
monovalent antibody structure devoid of the Fc region but has an antigen binding
site. The F(ab) fragments are used to block the endogenous Ig's-immunoglobulins.
However, F(ab’)2 fragments are obtained through the pepsin digestion of IgG
antibody. This digestion will remove most of the Fc region but will keep some of the
hinge region intact. This fragment has two antigen binding sites which are attached
by disulfide bonds. The F(ab’)2 fragments are smaller in size and thus have better
penetration. This antibody fragment also has a better antigen recognition feature,
as these antibody fragments avoid unspecific binding. Both of these antibody
fragments provide better results in the immunohistochemistry applications.
Antibody fragments have a very vast range of therapeutic applications. The field of
antibody fragments applications is just the revised or advanced version of
monoclonal antibody therapeutic applications. Antibody fragments are very useful
in medical diagnostics; specific antibody fragments are used for disease diagnosis.
In some cases, multiple antibody fragments are used to spot antigens specific to
cause a particular infectious disease. Antibody fragments are used to treat many
immune deficiencies, central nervous system disorders, and cardiovascular
diseases. Many antibody fragments are used to treat colorectal cancer and breast
cancer.
Antibody Fragments Market: Market Dynamics
With increasing incidences of various types of cancers, infectious diseases and in
turn immune deficiencies, there is going to be an increasing demand for antibody
fragments. Also, an increase in geriatric population has been observed worldwide.
Therefore, looking at the application prospects of antibody fragments, the market is
likely to boom over the forecast period. Antibody fragments are also expected to be
preferred compared to full-chain antibodies as the manufacturing and purification
costs of antibody fragments are less. Strict ICD-10 guidelines may restrain the use
of some antibody fragments for the treatment of a particular disease. However, new
developments in the clinical development of antibody fragments for some of the
deadliest diseases can give a massive opportunity for the antibody fragments
market over the forecast period.
Antibody Fragments Market: Region-wise Outlook and Key Players
The occurrence of cancer and other immunodeficiencies are observed at a higher
rate in North America compared to other regions. North America and Europe spend
a significant amount of money on drugs and therapies related to cancer. It is
estimated that North America is the largest market for antibody fragments, followed
by Europe, trailed by Asia-Pacific, Latin America and the Middle East and Africa. The