Annual Report 2017 | Page 21

DETECTING BLADDER CANCER EARLY
Published in Journal of Translational Medicine
Charles Rosser
YOSHIKO SHIMIZU | KAZUE TSUKIKAWA HIDEKI FURUYA | CHARLES ROSSER
A non-invasive bladder cancer detection test was developed by Charles Rosser , MD , MBA , director of Translational and Clinical Research and his colleagues . The test showed a strong overall performance when used on par ticipants in Japan .
“ The development of non-invasive tests that can accurately detect and monitor bladder cancer is clinically urgent ,” said Rosser . “ With the prolonged and invasive nature of follow-up and treatment strategies , bladder cancer is one of the most expensive malignancies to manage .”
The test results confrmed the presence of bladder cancer when evaluating samples with the chosen panel of biomarkers . The results reinforced the potential use of the biomarkers for detection of the disease .
BLADDER CANCER IN HAWAI ‘ I
MOST
MOST DEADLY
PEOPLE ARE
COMMON
CANCER
DIAGNOSED
CANCER
IN MEN
EACH YEAR
Hideki Furuya
ENZYME DISCOVERY IN COLON AND BREAST CANCERS
Published in Journal of Translational Medicine and Carcinogenesis
HIDEKI FURUYA | PAULETTE M . TAMASHIRO YOSHIKO SHIMIZU | KAYOKO IINO | RAFAEL PERES
Hideki Furuya , PhD , and collaborators found that the enzyme ( sphingosine kinase 1 ), which produces an infammatory lipid , plays an important role in colon and breast cancers . Specifcally , the most recent study found that sphingosine kinase 1 activates the immune cell ( macrophage ) to induce infammation leading to colon cancer . The fndings can potentially lead to an innovative immunotherapy for cancers in the near future .
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