THE 3D BIOPRINTING TISSUE ENGINEERING :
REVOLUTIONARY SOLUTION FOR HEART TRANSPLANTATION ORGAN DONOR
SHORTAGE BY USING HUMAN INDUCED PLURIPOTENS STEM CELLS (iPSCs) AS
RECELLULERIZATION MATERIAL ON PIG HEART
Khrisna Rangga P 1, Deddy Dwi S, Isma Dewi M, Hasna Okta A
AMSA Brawijaya University
Background/Introduction: Heart transplant is the only definitive treatment for end-stage heart disease
in the last 50 years. Despite the advances development in transplant technology, the main obstacle for
heart transplantations is the availability of donor organ. With more than 100,000 hearts has been
transplanted in the last decade, it still ranked 1 in donor shortage compared with other donor organ.
There is an emerge development in 3D biopriting tissue enginering that will allow us to construct whole
heart to end the heart donor sortage. The most robust and efficient way to construct 3D object is by
utilizing decellulerization and recellulerization technique.
Research Purpose: To develope the idea of usin