AMINO AMSA-Indonesia EAMSC 2016 | Page 193

Printable Organs Felix Hindarto, Kirti Anindita Suharsono & Alvian Gunawan Faculty Medicine of Atma Jaya Indonesia Three-dimensional printing is creating a 3D structure. It was first developed in the early 1990s at MIT by using a regular ink-jet print head. In a recent medical field, this method is used for creating living tissues and replacing the damaged ones, for example bone, skin, and other tissues. This whole process of 3D printing is made in vitro. The scaffold is made to match the extracellular matrix. Multi-potent stromal cells (MSC) then injected into the scaffold before implantation so that the duplicate tissue can “survive” in the body. The traditional tissue engineering strategy is to isolate stem cells from small tissue samples, mix them with growth factors, multiply them in the laboratory, and seed the cells onto scaffolds that direct cell proliferation and differentiation into functioning tissues. In 2009, 154,324 patients in the U.S. were waiting for an organ and only 27,996 of them (18%) received an organ transplant, and 8,863 (25 per day) died while on the waiting list. If this problem can be solved, fulfilling the demands can also reduce this mortality number efficiently. Printing complex organs have not been developed completely. Complex organs have a specific metabolic mechanisms in which cannot function properly without vascularization. Three-dimensional printing lets us produce custom-made medical products and equipment cheaply by decreasing the use of unnecessary resourc es. Doctors and patients can have a positive impact in terms of the time required for surgery. Patients will have more recovery time, and success of the surgery or implant as the progenitor cells are taken from the patients themselves so the transplant rejection can be minimized. “Fast” in 3D printing means that a product can be made within several hours with high resolution, accuracy, reliability, and repeatability of 3D printing technologies. So, no more waiting in line to save lives! Contact Name: Felix Hindarto, e-mail: hindarto_felix@yahoo.com, Phone: +6287851662272