Agri Kultuur June / Junie 2018 | Page 15

said he could not tell the difference between a wrap containing real chicken and one with the Beyond Meat chicken strips. Chef Alton Brown, tasting the product for Wired magazine, estimates the strips could replace chicken in “at least 30% of the existing chicken recipes floating around out there, and that’s a few hundred thousand (depending on who you ask).” Cellular Agriculture One way to get around the challenges of using plant proteins and fats to recreate the taste and texture of meat is to use real meat cells instead. Much like tissue engineering grows new organs in the lab, this approach grows muscle cells in culture. A team led by Mark J. Post of Maastricht University, in the Netherlands, was the first to unveil a lab- grown hamburger produced from thin strips of cultured beef. To create the strips, the researchers first isolate muscle cells from a piece of cow tissue. As the cells grow in culture, they form tubes 0.3 mm long, which the researchers then wrap around a cylinder of gel. The tubes grow into each other and naturally contract. Because of their circular arrangement, this contraction generates tension in the tubes, which encourages protein production and natural muscle tissue development into small fibre bundles. After 3 weeks, the researchers harvest a ring of tissue and slice it open to get a 25-mm-long strip. The process is not yet anywhere near as efficient as growing cow cells in a cow. The lab’s 85-g burger, unveiled in August 2013, used about 10,000 strips of muscle, and at the time, reportedly cost more than $300,000 to produce, grown on nutrient-rich medium containing glucose. And while tasters said the burger had an “intense taste close to meat” and a “familiar mouthfeel”, some noted that the muscle-only patty was a little lean. Post said the team is working on culturing fat cells to combine with the lab-grown muscle tissue. They also hope to tailor the culture conditions to get the composition of muscle proteins actin, myosin, and myoglobin that produces a natural taste—and with an efficiency to allow large-scale production. Though cult uring tissue requires energy to sterilize equipment and stir fermentation AgriKultuur |AgriCulture tanks, a 2011 life-cycle analysis suggests that, with even a little scale-up, the process could be better than a cow. Growing 1,000 kg of meat with nutrients from cyanobacteria would use much less energy, water, and land, and the process would generate dramatically less greenhouse gas than traditional beef production, according to the analysis. Applying standard biotechnology and engineering techniques to the process should bring the costs down, says Isha Datar, executive director of New Harvest, a New York based non-profit that awards grants to researchers working on “cellular agriculture”. Meat is not the only target for this technology. Datar says the group is trying to kick-start an industry for animal products made without animals. New Harvest recently collaborated with a start-up company called Clara Foods that is producing egg white proteins in yeast; the proteins can be fried just like a regular egg, added to cake batter, or whipped into a meringue. Within six months of starting at a San Francisco biotech accelerator, a cell biologist and his business partner developed the product and raised $1.75 million in seed funding. It remains to be seen whether these new products will sate our carnivorous desires. Investors seem willing to take a gamble, though, and Impossible Foods’s Brown is optimistic, noting that technology has eliminated animals from our daily lives before. About two hundred years ago, horses were the fastest transportation, one even winning a race against the first mechanized transportation, the steam locomotive. While horses have not gotten much faster since then, Brown says, the performance of mechanized transportation improves every year. He thinks Impossible Foods is in a similar position with respect to food. “We’re getting better every day, and we’re going to continue to get better”, he says, “... in ways the cows can’t.” Sources: Melissae Fellet: A Fresh Take on Fake Meat: https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC4827462/ Copyright © 2015 American Chemical Society. Open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non- commercial purposes. 15