Acta Dermato-Venereologica Suppl 219 AbstractPsoriasis2018 | Page 8

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5 th World Psoriasis & Psoriatic Arthritis Conference 2018
pus erythematosus : a single-center experience . Clin Rheumatol . 2017 Apr ; 36 ( 4 ): 879-884 . 2 . Inkeles MS , No D , Wu JJ . Clinical improvement of a patient with both amyopathic dermatomyositis and psoriasis following treatment with cyclosporine . Dermatol Online J . 2017 Aug 15 ; 23 ( 8 ) 3 . Kato Y , Yamamoto T . Development of psoriasis with relapse of dermatomyositis-associated interstitial lung disease . Int J Rheum Dis . 2017 May ; 20 ( 5 ): 660-661 . 4 . Ueno T , Kanzaki A et al . Association of psoriasis with Hashimoto ’ s thyroiditis , Sjögren ’ s syndrome and dermatomyositis . J Dermatol . 2016 Jun ; 43 ( 6 ): 711-2 .
P004 CHARACTERISTICS OF PSORIASIS IN OBESE PATIENTS VERSUS NON-OBESE PATIENTS ; A
MULTICENTER STUDY Omid Zargari 1 , Seyyede Zeinab Azimi 2 , Tara Barat 1 , Vahideh Lajevardi 3 , Ehsan Kazemnejad 4 , Mohamad Shahidi Dadras 1
1
Department of Dermatology , Skin Research Center , Shahid Beheshti University of Medical Sciences , Tehran , 2 Department of Dermatology and 4 Department of Biostatistics , Guilan University of Medical Sciences , Rasht , and 3 Department of Dermatology , Tehran University of Medical Sciences , Tehran , Iran
Introduction : Psoriasis is a common chronic inflammatory skin disease , which is gradually being recognized as a systemic inflammatory disorder . Psoriasis and obesity are strongly linked , but there is not enough data whether obese psoriatic patients present differently from non-obese psoriatic patients . Objective : To compare the phenotype , clinical features , severity , baseline comorbidities and laboratory findings among psoriatic patients with / without obesity . Methods : All the psoriatic patients , from three centers , who were receiving systemic therapy were included in the study . Patients were divided into two groups : those with obesity and those without obesity . Results : We included 497 patients : 154 ( 31 %) patients were obese and 343 ( 69 %) were non-obese . Obese patients had more comorbidities , particularly hyperlipidemia , followed by hypertension and diabetes . Fasting blood sugar and serum lipids were significantly higher among obese subjects . Conclusions : Given the differences between obese patients and non-obese patients , the former group should be followed and managed more closely and with specific attention . References : 1 . Kimball AB , Gladman D , Gelfand JM , Gordon K , Horn EJ et al . National Psoriasis Foundation clinical consensus on psoriasis comorbidities and recommendations for screening . J Am Acad Dermatol . 2008 ; 58 ( 6 ): 1031-42 . 2 . Love TJ , Qureshi AA , Karlson EW , Gelfand JM , Choi HK . Prevalence of the metabolic syndrome in psoriasis : results from the National Health and Nutrition Examination Survey , 2003 – 2006 . Arch Dermatol . 2011 ; 147 ( 4 ): 419-24
P005
PSORIASIS AND COMORBIDITY Veranika Liubiankova , Sviatlana Makarava Mogilev Regional Centre of Dermatology and Venerology
Introduction . In recent years special attention has been paid not only to the systemic nature of the process in psoriasis , but also to its association with comorbidities . Comorbidity is a regular combination of various diseases or conditions in one patient , it occurs in many inflammatory processes . Objectives : The study of the incidence of concomitant diseases in patients with psoriasis in relation to patients with allergic contact dermatitis , analysis by age group . Methods : A retrospective analysis of data of 804 patients , who were treated in 2016 – 2017 in Mogilev Regional Dermatology and Venerology Centre with different forms of psoriasis , was conducted . 492 males , 312 females . The mean age was 43.05 years . The control group consisted of patients with allergic contact dermatitis , comparable in age and sex , in an amount of 397 people . Results : Specific gravity and incidence of comorbidity in patients with psoriasis : cardiovascular damage 41 % ( 331 ), gastrointestinal tract - 30.4 % ( 245 ), endocrine system - 22.7 % ( 183 ), metabolic syndrome - 28.2 % ( 227 ), chronic otorhinolaryngological diseases - 11.4 % ( 92 ), diseases of urinary system - 6.2 % ( 50 ), respiratory system - 4.7 % ( 38 ). Significant differences between the groups were obtained for all the comorbidity except respiratory diseases . Psoriatic polyarthritis were observed in 219 patients ( 27.3 %), nail psoriasis – in 117 patients ( 14.6 %). The average body mass index in the psoriasis group was 27.2 , in the allergic contact dermatitis group - 25.3 . Significant differences between the groups were obtained for all the laboratory test changes except the general bilirubin , C-reactive protein and urinalysis . The percentage of diseases changed with increasing age : diseases of the cardiovascular system from 10 % to 87 %, gastrointestinal diseases from 20 % to 61 %, endocrine system diseases - from 14.5 % to 38 %, metabolic syndrome - from 11 % to 34 %, otorhinolaryngological diseases - from 15 % to 8.5 %, diseases of the urinary system - from 1.8 % to 8.5 %, respiratory system diseases – from 1.8 % to 13 %. Conclusions : The analysis showed that in patients with psoriasis the most frequent comorbidity are : cardiovascular and gastrointestinal diseases , endocrine disorders , polyarthritis , nail psoriasis and metabolic syndrome . A rather high risk of comorbidity is established , in comparison with the population , which can directly affects the severity of the course of the disease , the effectiveness of the therapy and life expectancy . References : 1 . Potekaev N ., Kruglova L . Psoriatic Disease . – Moscow . - 2014 . - P . 94 ( in Russian ) 2 . Cohen A . D ., Sherf M ., Vidavsky L ., Vardy D . A . Association between psoriasis and the metabolic syndrome . A crosssectional study // Dermatology .— 2008 .— Vol . 216 ( 2 ).— Р . 152 3 . Eng S ., Xing B ., Caro I ., Werther W . Selected cardiovascular diseases in psoriasis , nonpsoriasis , and efalizumabtreated psoriasis patients // Acad . Dermatol .— 2009 .— P . 3381
P006 RISK OF PERIODONTAL DISEASE IN PATIENTS WITH
CHRONIC PLAQUE PSORIASIS Veronica Lopez Castillo , Inmaculada Lopez Castillo , Pedro Rodriguez , Jose Maria Ricart Vaya Introduction : Psoriasis is a common , chronic , inflammatory , multisystem disease affecting approximately 2 % of population . It has been associated with certain diseases and there is a strong link between metabolic syndrome and psoriasis . Chronic periodontitis is an infectious disease resulting in inflammation within the supporting tissues of the teeth , progressive attachment loss , and bone resorption and clinically characterized by pocket formation and / or gingival recession . Psoriasis and chronic periodontitis share common risk factors and co-morbidities . Objective : The aim of our study was to determine how frequently chronic periodontitis is associated with patients with psoriasis compared to systemic healthy subjects and if its presence is associated to severity of psoriatic lesions . Methods : Baseline demographic data including sex , age , smoking habits , family history of psoriasis or periodontal disease was recorded in 40 psoriasis subjects and 40 healthy subjects . Information on comorbidities and pharmacological treatment , daily tooth brushing , the presence of gingival bleeding , location of skin lesions , weight and height were also evaluated . The periodontal clinical parameters probing depth , periodontal attachment level , plaque index and presence or absence of radiographic bone loss were recorded . The severity of psoriasis was assessed by Psoriasis Area and Severity Index . A complete blood test was asked for all subjects included in the study . www . medicaljournals . se / acta